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HYOU1 Antikörper (Middle Region)

HYOU1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782712
  • Target Alle HYOU1 Antikörper anzeigen
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Bindungsspezifität
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 43
    • 30
    Kaninchen
    Klonalität
    • 38
    • 36
    Polyklonal
    Konjugat
    • 27
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HYOU1 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 27
    • 24
    • 14
    • 14
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DREVQYLLNK AKFTKPRPRP KDKNGTRAEP PLNASASDQG EKVIPPAGQT
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against HYOU1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human HYOU1
    Top Product
    Discover our top product HYOU1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 999 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

  • Target
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Andere Bezeichnung
    HYOU1 (HYOU1 Produkte)
    Synonyme
    GRP-170 antikoerper, Grp170 antikoerper, HSP12A antikoerper, ORP-150 antikoerper, ORP150 antikoerper, AI415631 antikoerper, CBP-140 antikoerper, Cab140 antikoerper, Orp150 antikoerper, id:ibd5056 antikoerper, wu:fd14c05 antikoerper, zgc:56019 antikoerper, HYOU1 antikoerper, orp150 antikoerper, GRP170 antikoerper, hypoxia up-regulated 1 antikoerper, hypoxia up-regulated protein 1 antikoerper, hypoxia up-regulated 1 S homeolog antikoerper, HYOU1 antikoerper, Hyou1 antikoerper, hyou1 antikoerper, LOC100380749 antikoerper, hyou1.S antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal.
    Alias Symbols: DKFZp686N08236, ORP150, Grp170, HSP12A
    Protein Interaction Partner: CLU, HSPA8, UBC, MDM2, RNF2, EZH2, KIF13A, ARMCX3, GANAB, BCAR1, ATP6V1F, XRCC5, MCM7, MCM2, MSH6, XRCC6, ATP6V1B2, BIN1, UBD, env, OS9, NUP37, POLR1C, FBXO6, CDK2, SIRT7, SARM1, H2AFX, IKBKE, EXT2,
    Protein Size: 999
    Molekulargewicht
    108 kDa
    Gen-ID
    10525
    NCBI Accession
    NM_006389, NP_006380
    UniProt
    Q9Y4L1
    Pathways
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom
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