HIST1H1C Antikörper (Middle Region)

Produktnummer ABIN2782497

Produktdetails anti-HIST1H1C Antikörper

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST1H1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequenz: ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HIST1H1C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 213 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HIST1H1C

Target: HIST1H1C (Histone Cluster 1, H1c (HIST1H1C))

Andere Bezeichnung: HIST1H1C (HIST1H1C Produkte)

Synonyme: H1.2 antikoerper, H1C antikoerper, H1F2 antikoerper, H1s-1 antikoerper, 0610008C09Rik antikoerper, H1c antikoerper, H1f2 antikoerper, H1var1 antikoerper, His1a antikoerper, histone cluster 1 H1 family member c antikoerper, histone cluster 1, H1c antikoerper, HIST1H1C antikoerper, Hist1h1c antikoerper

Hintergrund: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H1.2, H1F2, MGC3992, H1C
Protein Interaction Partner: UBC, CEP250, ATRX, HIST1H3A, LEO1, PAF1, CUL4A, POLR2A, MDM2, ASB16, ASB9, SUZ12, EED, RNF2, APEH, SEC24D, TBCD, PARK2, VHL, UBD, ICAM1, CD81, IGSF8, EIF2AK2, ITGA4, IL7R, CSNK2A2, SMURF1, HIST1H2AD, H1FX, COPS5, CAND1, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD
Protein Size: 213

Molekulargewicht: 21 kDa

Gen-ID: 3006

NCBI Accession: NM_005319, NP_005310

UniProt: P16403