HIST1H1C Antikörper (Histone Cluster 1, H1c) (Middle Region)

Details for Product anti-HIST1H1C Antibody No. ABIN2782497, Anbieter: Anmelden zum Anzeigen
Antigen
  • HIST1H1C
  • H1.2
  • H1C
  • H1F2
  • H1s-1
  • 0610008C09Rik
  • H1c
  • H1f2
  • H1var1
  • His1a
  • H14
  • H1d
  • H1f4
  • Hist1h1c
  • Hist1h1e
  • histone cluster 1, H1c
  • histone cluster 1, H1.11L
  • histone cluster 1 H1 family member c
  • histone cluster 1, H1d
  • HIST1H1C
  • HIST1H111L
  • Hist1h1c
  • Hist1h1d
Epitop
Middle Region
11
10
8
7
2
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
37
8
8
Wirt
Kaninchen
37
Klonalität
Polyklonal
Konjugat
Dieser HIST1H1C Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
34
22
10
4
3
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN978000.
Sequenz ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS
Homologie Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 85%, Rat: 86%
Produktmerkmale This is a rabbit polyclonal antibody against HIST1H1C. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung HIST1H1C (HIST1H1C Antibody Abstract)
Hintergrund Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H1.2, H1F2, MGC3992, H1C
Protein Interaction Partner: UBC, CEP250, ATRX, HIST1H3A, LEO1, PAF1, CUL4A, POLR2A, MDM2, ASB16, ASB9, SUZ12, EED, RNF2, APEH, SEC24D, TBCD, PARK2, VHL, UBD, ICAM1, CD81, IGSF8, EIF2AK2, ITGA4, IL7R, CSNK2A2, SMURF1, HIST1H2AD, H1FX, COPS5, CAND1, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD
Protein Size: 213
Molekulargewicht 21 kDa
Gen-ID 3006
NCBI Accession NM_005319, NP_005310
UniProt P16403
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 213 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Histone Cluster 1, H1c (HIST1H1C) (Middle Region) antibody (ABIN2782497) WB Suggested Anti-HIST1H1C Antibody Titration: 0.2-1 ug/ml
Positive Cont...
Allgemeine Veröffentlichungen Kim, Choi, Heo, Kim, Levens, Kohno, Johnson, Brock, An: "Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription." in: The Journal of biological chemistry, Vol. 283, Issue 14, pp. 9113-26, 2008 (PubMed).

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