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RRM2B Antikörper (Middle Region)

RRM2B Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Pferd, Schwein, Hund, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782441
  • Target Alle RRM2B Antikörper anzeigen
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 39
    • 35
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Kaninchen, Pferd, Schwein, Hund, Meerschweinchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 51
    • 3
    Kaninchen
    Klonalität
    • 51
    • 3
    Polyklonal
    Konjugat
    • 22
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RRM2B Antikörper ist unkonjugiert
    Applikation
    • 47
    • 24
    • 13
    • 13
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Yeast: 93%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RRM2B. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human RRM2B
    Top Product
    Discover our top product RRM2B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeat freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
    Andere Bezeichnung
    RRM2B (RRM2B Produkte)
    Synonyme
    p53r2 antikoerper, RRM2B antikoerper, MTDPS8A antikoerper, MTDPS8B antikoerper, P53R2 antikoerper, p53R2 antikoerper, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antikoerper, ribonucleotide reductase regulatory TP53 inducible subunit M2B antikoerper, ribonucleotide reductase M2 B (TP53 inducible) antikoerper, rrm2b.S antikoerper, RRM2B antikoerper, rrm2b antikoerper, Rrm2b antikoerper
    Hintergrund
    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
    Protein Interaction Partner: RRM2B, ORC4, UBC, AICDA, RRM1, TP53, RRM2, MDM2, ATM, ZBTB17, MYC,
    Protein Size: 299
    Molekulargewicht
    32 kDa
    Gen-ID
    50484
    Pathways
    p53 Signalweg, Negative Regulation of intrinsic apoptotic Signaling
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