POFUT2 Antikörper (N-Term)

Produktnummer ABIN2782385

Produktdetails anti-POFUT2 Antikörper

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POFUT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GAASRRRYLL YDVNPPEGFN LRRDVYIRIA SLLKTLLKTE EWVLVLPPWG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POFUT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POFUT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 429 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-POFUT2 Antikörper (ABIN2782385)

Luo, Koles, Vorndam, Haltiwanger, Panin: "Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9393-9, (2006) (PubMed).

Details zu POFUT2

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Andere Bezeichnung: POFUT2 (POFUT2 Produkte)

Synonyme: C21orf80 antikoerper, FUT13 antikoerper, fc46a11 antikoerper, wu:fc46a11 antikoerper, zgc:194822 antikoerper, 2310011G23Rik antikoerper, AI256847 antikoerper, BC003494 antikoerper, protein O-fucosyltransferase 2 antikoerper, POFUT2 antikoerper, pofut2 antikoerper, Pofut2 antikoerper

Hintergrund: POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM].
Alias Symbols: C21orf80, FUT13
Protein Interaction Partner: USP22,
Protein Size: 429

Molekulargewicht: 50 kDa

Gen-ID: 23275

NCBI Accession: NM_133635, NP_598368

UniProt: Q9Y2G5