UBASH3A Antikörper (Middle Region)

Produktnummer ABIN2782357

Produktdetails anti-UBASH3A Antikörper

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schwein, Saccharomyces cerevisiae, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBASH3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PCSLPRRSRG IKDFENDPPL SSCGIFQSRI AGDALLDSGI RISSVFASPA

Homologie: Cow: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%, Yeast: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against UBASH3A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBASH3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 661 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBASH3A

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Andere Bezeichnung: UBASH3A (UBASH3A Produkte)

Synonyme: UBASH3A antikoerper, CLIP4 antikoerper, STS-2 antikoerper, TULA antikoerper, TULA-1 antikoerper, 5830413C03Rik antikoerper, C330001M22 antikoerper, Sts-2 antikoerper, ubiquitin associated and SH3 domain containing A antikoerper, ubiquitin associated and SH3 domain containing, A antikoerper, UBASH3A antikoerper, Ubash3a antikoerper

Hintergrund: UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It also promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Alias Symbols: CLIP4, STS-2, TULA, TULA-1
Protein Interaction Partner: KRT40, SF3B4, SPRY2, DAZAP2, TP53BP2, REL, TRIM37, KCNE1, CBS, UBC, CRK, UBASH3B, PARK2, CBL, ABCE1, gag, AIFM1, EGFR, ALK, DNM1, UBB, UBE2L3,
Protein Size: 661

Molekulargewicht: 74 kDa

Gen-ID: 53347

NCBI Accession: NM_018961, NP_061834

UniProt: P57075