ICAM5 Antikörper (N-Term)

Produktnummer ABIN2782226

Produktdetails anti-ICAM5 Antikörper

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICAM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRNGTQRGLR WLARQLVDIR EPETQPVCFF RCARRTLQAR GLIRTFQRPD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ICAM5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ICAM5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 924 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ICAM5 Antikörper (ABIN2782226)

Tian, Lappalainen, Autero, Hänninen, Rauvala, Gahmberg: "Shedded neuronal ICAM-5 suppresses T-cell activation." in: Blood, Vol. 111, Issue 7, pp. 3615-25, (2008) (PubMed).

Details zu ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Andere Bezeichnung: ICAM5 (ICAM5 Produkte)

Synonyme: TLCN antikoerper, TLN antikoerper, CD50 antikoerper, ICAM-3 antikoerper, Icam3 antikoerper, Tlcn antikoerper, ICAM5 antikoerper, icam5 antikoerper, tlcn antikoerper, tln antikoerper, intercellular adhesion molecule 5 antikoerper, intercellular adhesion molecule 5, telencephalin antikoerper, intercellular adhesion molecule 5 L homeolog antikoerper, ICAM5 antikoerper, Icam5 antikoerper, LOC100511183 antikoerper, icam5.L antikoerper

Hintergrund: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TLCN, TLN
Protein Interaction Partner: FBXO6, PSEN2, ITGB2, ITGAL, PSEN1,
Protein Size: 924

Molekulargewicht: 95 kDa

Gen-ID: 7087

NCBI Accession: NM_003259, NP_003250

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location