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Protocadherin gamma Subfamily C, 3 (PCDHGC3) (C-Term) Antikörper

PCDHGC3 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782183
  • Target Alle Protocadherin gamma Subfamily C, 3 (PCDHGC3) Antikörper anzeigen
    Protocadherin gamma Subfamily C, 3 (PCDHGC3)
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 53
    • 10
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh)
    Wirt
    • 49
    • 4
    Kaninchen
    Klonalität
    • 50
    • 3
    Polyklonal
    Konjugat
    • 17
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 42
    • 28
    • 14
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IKDNGEPSLS TTATLTVSVT EDSPEARAEF PSGSAPREQK KNLTFYLLLS
    Homologie
    Cow: 92%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PCDHGC3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human PCDHGC3
    Top Product
    Discover our top product PCDHGC3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 934 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Protocadherin gamma Subfamily C, 3 (PCDHGC3)
    Andere Bezeichnung
    PCDHGC3 (PCDHGC3 Produkte)
    Synonyme
    PC43 antikoerper, PCDH-GAMMA-C3 antikoerper, PCDH2 antikoerper, Pcdh2 antikoerper, PCDHGA11 antikoerper, PCDHGC5 antikoerper, protocadherin gamma subfamily C, 3 antikoerper, PCDHGC3 antikoerper, Pcdhgc3 antikoerper
    Hintergrund
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. PCDHGC3 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Alias Symbols: PC43, PCDH-GAMMA-C3, PCDH2
    Protein Interaction Partner: UBC, MFSD3, HGD, APP,
    Protein Size: 934
    Molekulargewicht
    98 kDa
    Gen-ID
    5098
    NCBI Accession
    NM_002588, NP_002579
    UniProt
    Q9UN70
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