Lamin B Receptor Antikörper (Middle Region)

Produktnummer ABIN2782167

Produktdetails anti-Lamin B Receptor Antikörper

Target: Lamin B Receptor (LBR)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Yeast: 77%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LBR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LBR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 615 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Lamin B Receptor

Target: Lamin B Receptor (LBR)

Andere Bezeichnung: LBR (LBR Produkte)

Synonyme: CG17952 antikoerper, Dmel\\CG17952 antikoerper, dLBR antikoerper, sb:cb406 antikoerper, zgc:86649 antikoerper, wu:fb75h08 antikoerper, wu:fc47b04 antikoerper, wu:fd36b07 antikoerper, lbr-A antikoerper, Xp58 antikoerper, p58 gene antikoerper, LBR antikoerper, DHCR14B antikoerper, LMN2R antikoerper, PHA antikoerper, TDRD18 antikoerper, AI505894 antikoerper, ic antikoerper, Nbp60 antikoerper, lamin B receptor antikoerper, Lamin B receptor antikoerper, lamin B receptor S homeolog antikoerper, LBR antikoerper, lbr antikoerper, lbr.S antikoerper, Lbr antikoerper

Hintergrund: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Alias Symbols: DHCR14B, LMN2R, MGC9041, PHA
Protein Interaction Partner: UBC, EED, CLK3, HIPK4, LMNA, HNRNPR, EIF4A3, ILF2, HNRNPU, DHX15, DHX9, KCND3, PPP1CC, PPP1CB, PPP1CA, TCF3, ARRB2, SUMO2, HIST2H4A, HIST1H3A, tat, CBX5, SRPK1, FNBP4, AKAP8L, YWHAG, CBX3, LBR, PRM1, LMNB1, MECP2,
Protein Size: 615

Molekulargewicht: 71 kDa

Gen-ID: 3930

NCBI Accession: NM_002296, NP_002287

UniProt: Q14739