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ABCA1 Antikörper (Middle Region)

ABCA1 Reaktivität: Maus, Human, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781512
  • Target Alle ABCA1 Antikörper anzeigen
    ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
    Bindungsspezifität
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Maus, Human, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Schwein, Kaninchen
    Wirt
    • 38
    • 14
    • 6
    • 2
    Kaninchen
    Klonalität
    • 40
    • 20
    Polyklonal
    Konjugat
    • 36
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ABCA1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP ESRETDLLSG MDGKGSYQLK
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Abca1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide corresponding to a region of Mouse
    Top Product
    Discover our top product ABCA1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 2261 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: "ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis." in: Cell metabolism, Vol. 18, Issue 2, pp. 225-38, (2013) (PubMed).

  • Target
    ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
    Andere Bezeichnung
    Abca1 (ABCA1 Produkte)
    Synonyme
    ABC-1 antikoerper, ABC1 antikoerper, CERP antikoerper, HDLDT1 antikoerper, TGD antikoerper, ABCA1 antikoerper, Abc1 antikoerper, ATP-binding cassette A1 antikoerper, Arabidopsis thaliana ATP-binding cassette A1 antikoerper, AtABCA1 antikoerper, im:7136239 antikoerper, sb:cb407 antikoerper, wu:fa07e06 antikoerper, zgc:171581 antikoerper, ATP binding cassette subfamily A member 1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1 antikoerper, ATP-binding cassette A1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1B antikoerper, ABCA1 antikoerper, Abca1 antikoerper, abca1 antikoerper, abca1b antikoerper
    Hintergrund
    Abca1 is a cAMP-dependent and sulfonylurea-sensitive anion transporter. Abca1 is a key gatekeeper influencing intracellular cholesterol transport.
    Alias Symbols: Abc1
    Protein Interaction Partner: Sptlc1, Ubc,
    Protein Size: 2261
    Molekulargewicht
    254 kDa
    Gen-ID
    11303
    NCBI Accession
    NM_013454, NP_038482
    UniProt
    B1AWZ8
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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