ABCC3 Antikörper (Middle Region)

Produktnummer ABIN2781505

Produktdetails anti-ABCC3 Antikörper

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KVHMKGSVAY VPQQAWIQNC TLQENVLFGK ALNPKRYQQT LEACALLADL

Homologie: Dog: 77%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ABCC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1527 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ABCC3 Antikörper (ABIN2781505)

Jeong, Kim, Shin, Park, Oh, Kim, Moon, Choi, Jeong, Shin, Kim: "Increased serum bile acid concentration following low-dose chronic administration of thioacetamide in rats, as evidenced by metabolomic analysis." in: Toxicology and applied pharmacology, Vol. 288, Issue 2, pp. 213-22, (2015) (PubMed).

Details zu ABCC3

Target: ABCC3 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3))

Andere Bezeichnung: ABCC3 (ABCC3 Produkte)

Synonyme: ABC31 antikoerper, EST90757 antikoerper, MLP2 antikoerper, MOAT-D antikoerper, MRP3 antikoerper, cMOAT2 antikoerper, 1700019L09Rik antikoerper, Mlp2 antikoerper, Mrp3 antikoerper, ATP binding cassette subfamily C member 3 antikoerper, ATP-binding cassette, sub-family C (CFTR/MRP), member 3 antikoerper, ABCC3 antikoerper, Abcc3 antikoerper

Hintergrund: ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2
Protein Interaction Partner: UBC, MLH1,
Protein Size: 1527

Molekulargewicht: 168 kDa

Gen-ID: 8714

NCBI Accession: NM_003786, NP_003777

UniProt: O15438