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ECH1 Antikörper (N-Term)

ECH1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781318
  • Target Alle ECH1 Antikörper anzeigen
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Bindungsspezifität
    • 16
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    N-Term
    Reaktivität
    • 29
    • 18
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund
    Wirt
    • 41
    • 3
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 16
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ECH1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 24
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Sequenz
    PDHSYESLRV TSAQKHVLHV QLNRPNKRNA MNKVFWREMV ECFNKISRDA
    Homologie
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ECH1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ECH1
    Top Product
    Discover our top product ECH1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 328 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Xie, Zhang, Lei, Ouyang, Du: "Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 903258, (2014) (PubMed).

    Xie, Wang, Zhang, Li, Can, Qing, Kung, Zhang: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." in: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).

  • Target
    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
    Andere Bezeichnung
    ECH1 (ECH1 Produkte)
    Synonyme
    HPXEL antikoerper, Pxel antikoerper, AA617331 antikoerper, enoyl-CoA hydratase 1, peroxisomal antikoerper, enoyl CoA hydratase 1, peroxisomal antikoerper, enoyl-CoA hydratase 1 antikoerper, delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial antikoerper, enoyl-CoA hydratase 1, peroxisomal L homeolog antikoerper, enoyl coenzyme A hydratase 1, peroxisomal antikoerper, ech1 antikoerper, ECH1 antikoerper, LOC747511 antikoerper, ech1.L antikoerper, Ech1 antikoerper
    Hintergrund
    ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
    Alias Symbols: HPXEL
    Protein Interaction Partner: FAM9B, HUWE1, TRAF1, UBC, MDM2, PPP6R3, IQCB1, STAT3, PEX5, EEF1D, DNAJB11, HNRNPUL1, OPA1, APP, HTT, EEF1G, HDAC5, ICT1, TLR10, PAFAH1B3, SERPINB9, CSTF2, TIMP1,
    Protein Size: 328
    Molekulargewicht
    36 kDa
    Gen-ID
    1891
    NCBI Accession
    NM_001398, NP_001389
    UniProt
    Q13011
    Pathways
    Monocarboxylic Acid Catabolic Process
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