PCSK5 Antikörper (Middle Region)
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- Target Alle PCSK5 Antikörper anzeigen
- PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PCSK5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- CAGAGADGCI NCTEGYFMED GRCVQSCSIS YYFDHSSENG YKSCKKCDIS
- Homologie
- Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PCSK5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PCSK5
- Top Product
- Discover our top product PCSK5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 913 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." in: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).
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VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." in: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).
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- Target
- PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
- Andere Bezeichnung
- PCSK5 (PCSK5 Produkte)
- Synonyme
- PC5 antikoerper, PC6 antikoerper, PC6A antikoerper, SPC6 antikoerper, subtilase antikoerper, PC5/6A antikoerper, PC5A antikoerper, b2b1549Clo antikoerper, b2b585Clo antikoerper, Pc5 antikoerper, fur2 antikoerper, spc6 antikoerper, spc6A antikoerper, MGC98915 antikoerper, PCSK5 antikoerper, pc6 antikoerper, spc6a antikoerper, pcsk5 antikoerper, zgc:165659 antikoerper, proprotein convertase subtilisin/kexin type 5 antikoerper, proprotein convertase subtilisin/kexin type 5 S homeolog antikoerper, proprotein convertase subtilisin/kexin type 5b antikoerper, PCSK5 antikoerper, Pcsk5 antikoerper, pcsk5.S antikoerper, LOC528098 antikoerper, pcsk5 antikoerper, pcsk5b antikoerper
- Hintergrund
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PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PC5, PC6, PC6A, SPC6
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-7, LCE3C, KRTAP4-12, NUFIP2, GLRX3, STK16, MEOX2, KRTAP5-9, env, Hoxa1, ATN1, UBC, CACNA1A, APPBP2, AMH, REN, PTPRM, PMCH, ITGA6,
Protein Size: 913 - Molekulargewicht
- 89 kDa
- Gen-ID
- 5125
- NCBI Accession
- NM_006200, NP_006191
- UniProt
- Q92824
- Pathways
- Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones
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