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PCSK5 Antikörper (Middle Region)

PCSK5 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781306
  • Target Alle PCSK5 Antikörper anzeigen
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Bindungsspezifität
    • 14
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen
    Wirt
    • 36
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    • 1
    Polyklonal
    Konjugat
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCSK5 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 20
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    CAGAGADGCI NCTEGYFMED GRCVQSCSIS YYFDHSSENG YKSCKKCDIS
    Homologie
    Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PCSK5. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PCSK5
    Top Product
    Discover our top product PCSK5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 913 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Szumska, Pieles, Essalmani, Bilski, Mesnard, Kaur, Franklyn, El Omari, Jefferis, Bentham, Taylor, Schneider, Arnold, Johnson, Tymowska-Lalanne, Stammers, Clarke, Neubauer, Morris, Brown, Shaw-Smith, Cama, Capra, Ragoussis, Constam, Seidah, Prat, Bhattacha: "VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5." in: Genes & development, Vol. 22, Issue 11, pp. 1465-77, (2008) (PubMed).

  • Target
    PCSK5 (Proprotein Convertase Subtilisin/kexin Type 5 (PCSK5))
    Andere Bezeichnung
    PCSK5 (PCSK5 Produkte)
    Synonyme
    PC5 antikoerper, PC6 antikoerper, PC6A antikoerper, SPC6 antikoerper, subtilase antikoerper, PC5/6A antikoerper, PC5A antikoerper, b2b1549Clo antikoerper, b2b585Clo antikoerper, Pc5 antikoerper, fur2 antikoerper, spc6 antikoerper, spc6A antikoerper, MGC98915 antikoerper, PCSK5 antikoerper, pc6 antikoerper, spc6a antikoerper, pcsk5 antikoerper, zgc:165659 antikoerper, proprotein convertase subtilisin/kexin type 5 antikoerper, proprotein convertase subtilisin/kexin type 5 S homeolog antikoerper, proprotein convertase subtilisin/kexin type 5b antikoerper, PCSK5 antikoerper, Pcsk5 antikoerper, pcsk5.S antikoerper, LOC528098 antikoerper, pcsk5 antikoerper, pcsk5b antikoerper
    Hintergrund
    PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. PCSK5 mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PC5, PC6, PC6A, SPC6
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-7, LCE3C, KRTAP4-12, NUFIP2, GLRX3, STK16, MEOX2, KRTAP5-9, env, Hoxa1, ATN1, UBC, CACNA1A, APPBP2, AMH, REN, PTPRM, PMCH, ITGA6,
    Protein Size: 913
    Molekulargewicht
    89 kDa
    Gen-ID
    5125
    NCBI Accession
    NM_006200, NP_006191
    UniProt
    Q92824
    Pathways
    Neurotrophin Signalübertragung, Regulation of Systemic Arterial Blood Pressure by Hormones
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