NR2E3 Antikörper (N-Term)
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- Target Alle NR2E3 Antikörper anzeigen
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NR2E3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- METRPTALMS STVAAAAPAA GAASRKESPG RWGLGEDPTG VSPSLQCRVC
- Homologie
- Cow: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E3
- Top Product
- Discover our top product NR2E3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 410 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." in: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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Novel NR2E3 mutations (R104Q, R334G) associated with a mild form of enhanced S-cone syndrome demonstrate compound heterozygosity." in: Ophthalmology, Vol. 112, Issue 12, pp. 2115, (2005) (PubMed).
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- Target
- NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))
- Andere Bezeichnung
- NR2E3 (NR2E3 Produkte)
- Synonyme
- ESCS antikoerper, PNR antikoerper, RNR antikoerper, RP37 antikoerper, rd7 antikoerper, LOC100228348 antikoerper, A930035N01Rik antikoerper, wu:fj55b07 antikoerper, zgc:103631 antikoerper, nuclear receptor subfamily 2 group E member 3 antikoerper, nuclear receptor subfamily 2, group E, member 3 antikoerper, NR2E3 antikoerper, Nr2e3 antikoerper, nr2e3 antikoerper
- Hintergrund
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NR2E3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. NR2E3 is a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome.This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PNR, RNR, rd7, ESCS, RP37
Protein Interaction Partner: BCL11A, SIN3A, DHX30, TBL3, MYBBP1A, NCOR1, HDAC3, RBL1, RBBP7, RBBP4, HDAC1, CDK9, VDR, DEDD2, RBFOX2, IRF9, ZNF232, SNAPC1, PPARG, HOXC13, NR3C1, ELAVL2, POLR3D, RARA, NR1D1, CRX, RXRB, RXRA,
Protein Size: 410 - Molekulargewicht
- 45 kDa
- Gen-ID
- 10002
- NCBI Accession
- NM_014249, NP_055064
- UniProt
- Q9Y5X4
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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