BRD7 Antikörper (C-Term)

Produktnummer ABIN2780896

Produktdetails anti-BRD7 Antikörper

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KELAQQVTPG DIVSTYGVRK AMGISIPSPV MENNFVDLTE DTEEPKKTDV

Homologie: Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against BRD7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BRD7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 651 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BRD7 Antikörper (ABIN2780896)

Zhou, Tan, Hershenson: "Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells." in: Respiratory physiology & neurobiology, Vol. 140, Issue 1, pp. 89-97, (2004) (PubMed).

Details zu BRD7

Target: BRD7 (Bromodomain Containing 7 (BRD7))

Andere Bezeichnung: BRD7 (BRD7 Produkte)

Synonyme: zgc:66347 antikoerper, wu:fc95f02 antikoerper, MGC79478 antikoerper, BRD7 antikoerper, BP75 antikoerper, CELTIX1 antikoerper, NAG4 antikoerper, Ptpn13ip antikoerper, bromodomain containing 7 L homeolog antikoerper, bromodomain containing 7 antikoerper, brd7.L antikoerper, brd7 antikoerper, BRD7 antikoerper, Brd7 antikoerper

Hintergrund: BRD7 is an activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. It induces dephosphorylation of GSK3B at 'Tyr-216'.
Alias Symbols: BP75, CELTIX1, NAG4
Protein Interaction Partner: UBC, Dvl1, HIST2H3C, BRD2, NEFL, BARD1, LRIF1, HAP1, TFAP4, TRIM24, SUMO2, SMARCE1, SMARCD1, SMARCC2, Bcl7b, CHD7, ARID2, RBFOX2, BCL7C, SMARCC1, SMARCA4, PCBD1, POU2F1, MYC, BRCA1, BHLHE40, HIST2H4A, HIST2H3A, BTBD2, RIF1, HNRNPUL1, HIST1H2AL, AGR2, PSMD
Protein Size: 651

Molekulargewicht: 74 kDa

Gen-ID: 29117

NCBI Accession: NM_013263, NP_037395

UniProt: Q9NPI1