MafF Antikörper (N-Term)

Produktnummer ABIN2780877

Produktdetails anti-MafF Antikörper

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MafF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVRELNRHLR GLSAEEVTRL KQRRRTLKNR GYAASCRVKR VCQKEELQKQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAFF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAFF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 164 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MafF

Target: MafF (MAFF) (Transcription Factor MafF (MAFF))

Andere Bezeichnung: MAFF (MAFF Produkte)

Synonyme: zgc:63868 antikoerper, MAFF antikoerper, U-MAF antikoerper, hMafF antikoerper, MAF bZIP transcription factor F antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F S homeolog antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) antikoerper, Maff antikoerper, maff antikoerper, MAFF antikoerper, maff.S antikoerper

Hintergrund: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: U-MAF, hMafF
Protein Interaction Partner: NFE2L2, PARP1, BACH2, BATF3, MAFF, NFE2L3, NFIL3, NFE2L1, MAFG, FOS, DDIT3, BACH1, ATF3, BATF2, MAFIP, OVOL1, SUMO2, GTF2A1L, HDAC5, PPARG, NR3C1, NFE2, NRF1, PSAP, PRRX1, HOXD12,
Protein Size: 164

Molekulargewicht: 18 kDa

Gen-ID: 23764

NCBI Accession: NM_152878, NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction