Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) (C-Term) Antikörper

Details zu Produkt Nr. ABIN2780605, Anbieter: Anmelden zum Anzeigen
Antigen
  • fc39c11
  • wu:fc39c11
  • zgc:110210
  • AF9
  • YEATS3
  • 2210011H10Rik
  • 2610012I03Rik
  • 3830408D16Rik
  • Af9
  • D4Ertd321e
  • Af-9
  • myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog (Drosophila)
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
  • mllt3
  • MLLT3
  • Mllt3
Epitop
C-Term
31
14
10
8
6
5
4
4
4
4
3
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
83
18
9
8
7
7
6
5
5
3
2
2
2
1
Wirt
Kaninchen
80
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
71
38
31
29
21
17
7
4
2
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human MLLT3
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN980125.
Sequenz ERHILQQIVN LIEETGHFHI TNTTFDFDLC SLDKTTVRKL QSYLETSGTS
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Produktmerkmale This is a rabbit polyclonal antibody against MLLT3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung MLLT3 (MLLT3 Antibody Abstract)
Hintergrund MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9,11)(p22,q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
Alias Symbols: AF9, FLJ2035, YEATS3
Protein Interaction Partner: CDK9, HSP90B1, EAF1, AFF4, ELL2, MED26, ELL, MLLT3, AFF1, MLLT1, CDK6, CCNT1, CCNT2, APP, Cbx8, DOT1L, PAF1, KMT2A, BCOR, MLLT10, RNF2, AFF3, EEF2, ACACA, PCGF1, ELL3, NIPBL, SIRT1, LRIF1, RBM48, APPBP2, MCM6, PTN, EEF1A1, SGK1,
Protein Size: 342
Molekulargewicht 37 kDa
Gen-ID 4300
NCBI Accession NM_004529
UniProt Q6LEQ8
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 342 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 3 (MLLT3) (C-Term) Antikörper (ABIN2780605) WB Suggested Anti-MLLT3 Antibody Titration: 0.2-1 ug/ml
Positive Control...