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KLF4 Antikörper (C-Term)

KLF4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780577
  • Target Alle KLF4 Antikörper anzeigen
    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
    Bindungsspezifität
    • 13
    • 13
    • 11
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 110
    • 30
    • 21
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 91
    • 23
    • 1
    Kaninchen
    Klonalität
    • 82
    • 33
    Polyklonal
    Konjugat
    • 74
    • 8
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KLF4 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 59
    • 50
    • 25
    • 23
    • 21
    • 14
    • 12
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AGCGKTYTKS SHLKAHLRTH TGEKPYHCDW DGCGWKFARS DELTRHYRKH
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KLF4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4
    Top Product
    Discover our top product KLF4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 470 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Natesampillai, Kerkvliet, Leung, Veldhuis: "Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 2, pp. E385-91, (2008) (PubMed).

  • Target
    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))
    Andere Bezeichnung
    KLF4 (KLF4 Produkte)
    Synonyme
    EZF antikoerper, GKLF antikoerper, Gklf antikoerper, Zie antikoerper, KLF4 antikoerper, biklf antikoerper, biklf-A antikoerper, Kruppel like factor 4 antikoerper, Kruppel-like factor 4 (gut) antikoerper, Kruppel-like factor 4 antikoerper, Kruppel-like factor 4 (gut) L homeolog antikoerper, KLF4 antikoerper, Klf4 antikoerper, klf4 antikoerper, klf4.L antikoerper
    Hintergrund
    The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
    Alias Symbols: EZF, GKLF
    Protein Interaction Partner: EP300, CREBBP, SETD7, CTBP1, Dlg4, APP, CUL2, VHL, UBC, TCEB2, SP1, RELA, PRKCD, PPARG, SMARCA4, HDAC2, HDAC7, KAT5, HDAC1, HDAC5, ELK1, KLF6, TP53,
    Protein Size: 470
    Molekulargewicht
    50 kDa
    Gen-ID
    9314
    NCBI Accession
    NM_004235, NP_004226
    UniProt
    O43474
    Pathways
    Peptide Hormone Metabolism, Stem Cell Maintenance
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