ZNF76 Antikörper (N-Term)

Produktnummer ABIN2780514

Produktdetails anti-ZNF76 Antikörper

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF76 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ KEALSFEDGQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF76. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF76

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 570 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF76

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Andere Bezeichnung: ZNF76 (ZNF76 Produkte)

Synonyme: 2810027J07 antikoerper, BC025615 antikoerper, Znf76 antikoerper, D6S229E antikoerper, ZNF523 antikoerper, Zfp523 antikoerper, zinc finger protein 523 antikoerper, zinc finger protein 76 antikoerper, Zfp523 antikoerper, ZNF76 antikoerper

Hintergrund: ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
Alias Symbols: ZNF523, Zfp523, D6S229E
Protein Interaction Partner: SMAD1, UBC, TBP, HDAC1, EP300, CAND1, ELAVL1, Pias1,
Protein Size: 570

Molekulargewicht: 62 kDa

Gen-ID: 7629

NCBI Accession: NM_003427, NP_003418

UniProt: P36508