TFAP2B Antikörper (C-Term)

Produktnummer ABIN2780496

Produktdetails anti-TFAP2B Antikörper

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAP2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALTALQNYLT EALKGMDKMF LNNTTTNRHT SGEGPGSKTG DKEEKHRK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 82%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TFAP2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 460 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TFAP2B

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Andere Bezeichnung: TFAP2B (TFAP2B Produkte)

Synonyme: TFAP2B antikoerper, AP-2B antikoerper, Tcfap2b antikoerper, AP2 antikoerper, si:dkey-5e16.1 antikoerper, zgc:110163 antikoerper, AP-1beta1 antikoerper, AP-2beta antikoerper, AP-beta1 antikoerper, AP1beta1 antikoerper, AP2beta2 antikoerper, BAD1 antikoerper, BAP antikoerper, Beta-adaptin antikoerper, CG12532 antikoerper, Dmel\\CG12532 antikoerper, bap antikoerper, beta1/2 antikoerper, cg12532 antikoerper, AI606113 antikoerper, AP-2(beta) antikoerper, E130018K07Rik antikoerper, AP2-B antikoerper, ap-2b antikoerper, ap2-b antikoerper, tfap2beta antikoerper, transcription factor AP-2 beta antikoerper, beta-adaptin antikoerper, putative beta-adaptin antikoerper, Adaptor Protein complex 1/2, beta subunit antikoerper, transcription factor AP-2 beta L homeolog antikoerper, TFAP2B antikoerper, Tfap2b antikoerper, tfap2b antikoerper, Tc00.1047053509799.10 antikoerper, Tc00.1047053506247.200 antikoerper, LINJ_36_7080 antikoerper, LBRM_35_7120 antikoerper, LMJF_36_6770 antikoerper, Tcfap2b antikoerper, AP-1-2beta antikoerper, Tsp_09571 antikoerper, tfap2b.L antikoerper

Hintergrund: TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes.This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-144 AU141084.1 1-144 145-1684 BC037225.1 1-1540 1685-5370 AL049693.16 11928-15613 5371-5770 BU738725.1 18-417 c
Alias Symbols: AP-2B, AP2-B, MGC21381
Protein Interaction Partner: YEATS4, UBC, KCTD1, UBE2I, SUMO1, SSBP4, LZTR1, VPS11, HIST1H2AC, CITED4, MYC, CITED2, CITED1,
Protein Size: 460

Molekulargewicht: 50 kDa

Gen-ID: 7021

NCBI Accession: NM_003221, NP_003212

UniProt: Q92481

Pathways: Carbohydrate Homeostasis, Synaptic Membrane