Recoverin Antikörper (C-Term)

Produktnummer ABIN2780450

Produktdetails anti-Recoverin Antikörper

Target: Recoverin (RCVRN)

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Recoverin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK

Homologie: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 75%, Rabbit: 79%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against RCV1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RCV1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 200 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Recoverin

Target: Recoverin (RCVRN)

Andere Bezeichnung: RCV1 (RCVRN Produkte)

Synonyme: RCV1 antikoerper, CAR antikoerper, S-modulin antikoerper, Rcv1 antikoerper, rcv1 antikoerper, rcvrn antikoerper, recoverin antikoerper, reco antikoerper, recoverin antikoerper, recoverin, gene 2 S homeolog antikoerper, recoverin, gene 2 L homeolog antikoerper, Recoverin antikoerper, RCVRN antikoerper, Rcvrn antikoerper, rcvrn.2.S antikoerper, rcvrn.2.L antikoerper, reco antikoerper

Hintergrund: RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.
Alias Symbols: RCV1, RCVRN
Protein Interaction Partner: GIT2, TGFBR2, SMAD3, IL15RA, TOP1, PQBP1, CAV1, GRK5, GRK6, GRK1, ADRBK1,
Protein Size: 200

Molekulargewicht: 23 kDa

Gen-ID: 5957

NCBI Accession: NM_002903, NP_002894

UniProt: Q53XL0

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction