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IRF1 Antikörper (C-Term)

IRF1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780409
  • Target Alle IRF1 Antikörper anzeigen
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 88
    • 47
    • 33
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf, Pferd
    Wirt
    • 91
    • 7
    • 1
    • 1
    Kaninchen
    Klonalität
    • 83
    • 17
    Polyklonal
    Konjugat
    • 49
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF1 Antikörper ist unkonjugiert
    Applikation
    • 88
    • 33
    • 13
    • 12
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against IRF1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of IRF1
    Top Product
    Discover our top product IRF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 325 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Andere Bezeichnung
    IRF1 (IRF1 Produkte)
    Synonyme
    irf1 antikoerper, zgc:136945 antikoerper, IRF1 antikoerper, irf11 antikoerper, zgc:103566 antikoerper, IRF-1 antikoerper, MAR antikoerper, AU020929 antikoerper, Irf-1 antikoerper, interferon regulatory factor 1 antikoerper, interferon regulatory factor 1a antikoerper, interferon regulatory factor 1b antikoerper, IRF1 antikoerper, irf1a antikoerper, irf1b antikoerper, Irf1 antikoerper
    Hintergrund
    IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
    Alias Symbols: IRF-1, MAR
    Protein Interaction Partner: SUMO2, SUMO3, IRF2, KAT2B, EP300, PRDM1, UBC, BIRC3, MDM2, HIST1H3A, CBL, HSP90AA1, HSPA1A, Tbk1, STUB1, SPI1, QARS, IRF8, CDKN1B, TRIM28, SET, SP2, IRF9, YBX1, NPM1, TRMT2A, HCFC1, SEC63, KEAP1, TRAF3, CREBBP, tat, SMARCA4, STAT1, HMGA1, RELA, NFKB1, KAT
    Protein Size: 325
    Molekulargewicht
    36 kDa
    Gen-ID
    3659
    NCBI Accession
    NM_002198, NP_002189
    UniProt
    P10914
    Pathways
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagie
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