Atrophin 1 Antikörper (N-Term)

Produktnummer ABIN2780387

Produktdetails anti-Atrophin 1 Antikörper

Target: Atrophin 1 (ATN1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Atrophin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KTRQNKDSMS MRSGRKKEAP GPREELRSRG RASPGGVSTS SSDGKAEKSR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATN1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1190 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Atrophin 1

Target: Atrophin 1 (ATN1)

Andere Bezeichnung: ATN1 (ATN1 Produkte)

Synonyme: B37 antikoerper, D12S755E antikoerper, DRPLA antikoerper, HRS antikoerper, NOD antikoerper, Atr1 antikoerper, Drpla antikoerper, atrophin-1 antikoerper, RERE antikoerper, ATN1 antikoerper, atrophin 1 antikoerper, ATN1 antikoerper, Atn1 antikoerper

Hintergrund: Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within ATN1. The protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Alias Symbols: B37, D12S755E, DRPLA, NOD, HRS
Protein Interaction Partner: WWOX, Dlg4, SIAH1, HINFP, LRP2, RBFOX1, EFEMP2, NOC2L, RCHY1, ZMYND8, RBFOX2, KAT6B, SSPO, RAD54L2, ZSWIM8, WDR5, WWP2, WWP1, RBPMS, SPAG5, FBLN5, BAIAP2, PSME3, CBFA2T2, CHRD, NCK2, LTBP4, RBM10, KAT6A, BAG6, PRRC2A, TRIP6, TEP1, SLIT1, SIAH2, PSMA3, PLS
Protein Size: 1190

Molekulargewicht: 125 kDa

Gen-ID: 1822

NCBI Accession: NM_001940, NP_001931

UniProt: P54259