PRDM1 Antikörper (N-Term)

Produktnummer ABIN2780353

Produktdetails anti-PRDM1 Antikörper

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKMDMEDADM TLWTEAEFEE KCTYIVNDHP WDSGADGGTS VQAEASLPRN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDM1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 789 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: PRDM1 (PRDM1 Produkte)

Synonyme: GB11750 antikoerper, CG5249 antikoerper, Dmel\\CG5249 antikoerper, blimp-1 antikoerper, dBlimp-1 antikoerper, dBlimp1 antikoerper, Blimp-1 antikoerper, Blimp1 antikoerper, nrd antikoerper, prdm1 antikoerper, ubo antikoerper, wu:fb99c12 antikoerper, zgc:91885 antikoerper, MGC52536 antikoerper, PRDM1 antikoerper, blimp1 antikoerper, xblimp1 antikoerper, prdi-bf1 antikoerper, BLIMP1 antikoerper, PRDI-BF1 antikoerper, ZNFPR1A1 antikoerper, PR/SET domain 1 antikoerper, probable serine/threonine-protein kinase DDB_G0282963 antikoerper, CG5249 gene product from transcript CG5249-RF antikoerper, blimp-1 antikoerper, PR domain containing 1a, with ZNF domain antikoerper, PR domain 1 S homeolog antikoerper, B lymphocyte induced maturation protein 1 antikoerper, PR domain 1 antikoerper, PR domain containing 1, with ZNF domain antikoerper, PRDM1 antikoerper, LOC408295 antikoerper, Blimp-1 antikoerper, CpipJ_CPIJ007425 antikoerper, prdm1a antikoerper, prdm1.S antikoerper, prdm1 antikoerper, Prdm1 antikoerper

Hintergrund: PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Alias Symbols: BLIMP1, PRDI-BF1
Protein Interaction Partner: PRMT5, SENP1, EHMT2, PIAS1, SUMO1, IRF2, IRF1, HDAC2, HDAC1, HIST1H1A, MS4A1, HSP90AA1, ATXN1, ELAVL1, KDM1A, IRF4, TLE2, TLE1, AES, PRMT7, HIST2H3A,
Protein Size: 789

Molekulargewicht: 88 kDa

Gen-ID: 639

NCBI Accession: NM_001198, NP_001189

UniProt: O75626

Pathways: Regulation of Muscle Cell Differentiation