BACH1 Antikörper (C-Term)

Produktnummer ABIN2780352

Produktdetails anti-BACH1 Antikörper

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BACH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PPCARGNSEP GYARGQESQQ MSTATSEQAG PAEQCRQSGG ISDFCQQMTD

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BACH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BACH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 736 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BACH1

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Andere Bezeichnung: BACH1 (BACH1 Produkte)

Synonyme: zgc:112205 antikoerper, BACH1 antikoerper, 6230421P05Rik antikoerper, AI323795 antikoerper, BACH-1 antikoerper, BTB domain and CNC homolog 1 antikoerper, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b antikoerper, BTB and CNC homology 1, basic leucine zipper transcription factor 1 antikoerper, BACH1 antikoerper, bach1b antikoerper, bach1 antikoerper, Bach1 antikoerper

Hintergrund: BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.
Alias Symbols: BACH-1
Protein Interaction Partner: NFE2L2, BRCA1, SMAD3, FBXL17, NLK, UBC, MAFF, MAFB, MAFG, DDIT3, ATF2, CSNK1A1, ANAPC5, PALB2, TOPBP1, NBN, MRE11A, MLH1, BARD1, Bach1, HMMR, BRCA2, BRCC3, XPO1, NCOR1, MAFK, TP53, HDAC1, PATZ1, RBCK1, PARK2,
Protein Size: 736

Molekulargewicht: 82 kDa

Gen-ID: 571

NCBI Accession: NM_001186, NP_001177

UniProt: O14867