SOX9 Antikörper (SRY (Sex Determining Region Y)-Box 9) (C-Term)

Details for Product anti-SOX9 Antibody No. ABIN2780338, Anbieter: Anmelden zum Anzeigen
Antigen
  • LOC100227849
  • SOX9
  • CMD1
  • CMPD1
  • SRA1
  • SOX-9
  • 2010306G03Rik
  • AV220920
  • mKIAA4243
  • SRY-box 9
  • transcription factor SOX-9
  • SRY-box 10
  • SRY (sex determining region Y)-box 9
  • SRY box 9
  • SOX9
  • LOC100227849
  • SOX10
  • Sox9
Epitop
C-Term
18
16
15
15
14
14
14
13
11
9
9
6
5
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Zebrafisch
208
60
39
15
9
8
5
4
4
4
3
3
2
2
2
2
1
1
1
1
Wirt
Kaninchen
140
67
5
Klonalität
Polyklonal
Konjugat
Dieser SOX9 Antikörper ist unkonjugiert
6
6
6
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Western Blotting (WB)
168
96
77
54
53
29
22
14
8
7
5
5
4
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SOX9
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984286.
Sequenz AGQGTGLYST FTYMNPAQRP MYTPIADTSG VPSIPQTHSP QHWEQPVYTQ
Homologie Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
Produktmerkmale This is a rabbit polyclonal antibody against SOX9. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung SOX9 (SOX9 Antibody Abstract)
Hintergrund SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1, CMPD1, SRA1
Protein Interaction Partner: ZBTB7A, SCX, HERC1, UBC, SOX9, ATP6V1H, ctnnb1-a, RUNX2, SMAD3, SMAD2, EP300, CREB3L4, SPEN, KPNB1, TRAF2, CREBBP, MED12, NR5A1, MAF, HSPA1A, CREB1,
Protein Size: 509
Molekulargewicht 56 kDa
Gen-ID 6662
NCBI Accession NM_000346, NP_000337
UniProt P48436
Forschungsgebiet Organogenesis, Reproduction, Lineage Markers, Transcription Factors
Pathways EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 509 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-SRY (Sex Determining Region Y)-Box 9 (SOX9) (C-Term) antibody (ABIN2780338) WB Suggested Anti-SOX9 Antibody Titration: 0.2-1 ug/ml
Positive Control:...
Produkt verwendet in: Lau, Lee, Chang: "Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii." in: Biology of reproduction, Vol. 88, Issue 6, pp. 150, 2013 (PubMed).

Allgemeine Veröffentlichungen Vidal, Ortonne, Schedl: "SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms." in: Journal of cutaneous pathology, Vol. 35, Issue 4, pp. 373-9, 2008 (PubMed).

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