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SUZ12 Antikörper (Middle Region)

SUZ12 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schwein WB, IHC, ChIP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779689
  • Target Alle SUZ12 Antikörper anzeigen
    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
    Bindungsspezifität
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 42
    • 23
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schwein
    Wirt
    • 37
    • 7
    Kaninchen
    Klonalität
    • 26
    • 18
    Polyklonal
    Konjugat
    • 33
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SUZ12 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
    Sequenz
    TGETNDKSTA PIAKPLATRN SESLHQENKP GSVKPTQTIA VKESLTTDLQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SUZ12
    Top Product
    Discover our top product SUZ12 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 739 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
    Andere Bezeichnung
    SUZ12 (SUZ12 Produkte)
    Synonyme
    fc31h10 antikoerper, im:7153578 antikoerper, si:dkey-10p5.2 antikoerper, suz12 antikoerper, wu:fc31h10 antikoerper, 2610028O16Rik antikoerper, AI195385 antikoerper, AU016842 antikoerper, AW536442 antikoerper, D11Ertd530e antikoerper, mKIAA0160 antikoerper, Xsuz12 antikoerper, chet9 antikoerper, jjaz1 antikoerper, CHET9 antikoerper, ChET 9 protein antikoerper, JJAZ1 antikoerper, suz12l antikoerper, zgc:100863 antikoerper, SUZ12 polycomb repressive complex 2b subunit antikoerper, SUZ12 polycomb repressive complex 2 subunit antikoerper, suppressor of zeste 12 homolog (Drosophila) antikoerper, SUZ12 polycomb repressive complex 2 subunit S homeolog antikoerper, SUZ12 polycomb repressive complex 2a subunit antikoerper, suz12b antikoerper, Suz12 antikoerper, SUZ12 antikoerper, suz12.S antikoerper, suz12a antikoerper
    Hintergrund
    A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7,17)(p15,q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CHET9, JJAZ1, KIAA0160
    Protein Interaction Partner: FBXW11, EZH2, BRCA1, CDK5RAP2, RBM22, LUC7L, NHP2, H2AFY2, C17orf85, NAT10, ATAD3A, HEATR1, PTCD3, CHCHD3, CDKAL1, DDX56, GDAP1, LUC7L3, SF3B6, LUC7L2, NOP58, LIMA1, CDC40, CRNKL1, HP1BP3, STOML2, TRA2A, RBM15B, REPIN1, PRPF19, AKAP8L, TBL2, DAZAP1, PHGDH
    Protein Size: 739
    Molekulargewicht
    83 kDa
    Gen-ID
    23512
    NCBI Accession
    NM_015355, NP_056170
    UniProt
    Q15022
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