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Src Antikörper (N-Term)

Src Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779668
  • Target Alle Src Antikörper anzeigen
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    Bindungsspezifität
    • 28
    • 25
    • 25
    • 21
    • 21
    • 19
    • 15
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 234
    • 147
    • 124
    • 11
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen
    Wirt
    • 244
    • 22
    • 1
    Kaninchen
    Klonalität
    • 222
    • 45
    Polyklonal
    Konjugat
    • 124
    • 22
    • 19
    • 17
    • 14
    • 12
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Dieser Src Antikörper ist unkonjugiert
    Applikation
    • 198
    • 139
    • 68
    • 55
    • 53
    • 35
    • 30
    • 30
    • 23
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    MGSNKSKPKD ASQRRRSLEP AENVHGAGGG AFPASQTPSK PASADGHRGP
    Homologie
    Cow: 85%, Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SRC
    Top Product
    Discover our top product Src Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 536 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Src (Proto-oncogene tyrosine-protein kinase Src (Src))
    Andere Bezeichnung
    SRC (Src Produkte)
    Synonyme
    AW259666 antikoerper, pp60c-src antikoerper, C-src1 antikoerper, CG7524 antikoerper, D-Src64B antikoerper, D-src antikoerper, DSRC64 antikoerper, DSrc antikoerper, DSrc64 antikoerper, DSrc64B antikoerper, Dm SRC1 antikoerper, DmHD-358 antikoerper, Dmel\CG7524 antikoerper, Dsrc antikoerper, Dsrc64 antikoerper, Dsrc64B antikoerper, HD-358 antikoerper, MRE5 antikoerper, SRC 64B antikoerper, Src antikoerper, Src1 antikoerper, Src64 antikoerper, c-src antikoerper, dSrc antikoerper, dsrc antikoerper, src antikoerper, src1 antikoerper, src64 antikoerper, src64B antikoerper, src64b antikoerper, ASV antikoerper, SRC1 antikoerper, c-SRC antikoerper, p60-Src antikoerper, c-Src antikoerper, PP60C-SCR antikoerper, SDR antikoerper, SRC proto-oncogene, non-receptor tyrosine kinase antikoerper, uncharacterized LOC5574802 antikoerper, proto-oncogene tyrosine-protein kinase src antikoerper, Rous sarcoma oncogene antikoerper, Src oncogene at 64B antikoerper, SRC antikoerper, LOC5574802 antikoerper, CpipJ_CPIJ010659 antikoerper, Src antikoerper, Src64B antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: ASV, SRC1, c-SRC, p60-Src
    Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
    Protein Size: 536
    Molekulargewicht
    60 kDa
    Gen-ID
    6714
    NCBI Accession
    NM_198291, NP_938033
    UniProt
    P12931
    Pathways
    JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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