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POLR2B Antikörper (Middle Region)

POLR2B Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779656
  • Target Alle POLR2B Antikörper anzeigen
    POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 26
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 26
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser POLR2B Antikörper ist unkonjugiert
    Applikation
    • 25
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    FFRSVFYRSY KEQESKKGFD QEEVFEKPTR ETCQGMRHAI YDKLDDDGLI
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against POLR2B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human POLR2B
    Top Product
    Discover our top product POLR2B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1174 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Skalnik: "Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 609-18, (2008) (PubMed).

  • Target
    POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
    Andere Bezeichnung
    POLR2B (POLR2B Produkte)
    Synonyme
    Pol2rb antikoerper, Rpb140 antikoerper, Rpb2 antikoerper, POL2RB antikoerper, RPB2 antikoerper, hRPB140 antikoerper, hsRPB2 antikoerper, RNA polymerase II subunit B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa antikoerper, DNA-directed RNA polymerase II subunit RPB2 antikoerper, polymerase (RNA) II (DNA directed) polypeptide B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog antikoerper, POLR2B antikoerper, polr2b antikoerper, LOC100640211 antikoerper, Polr2b antikoerper, polr2b.L antikoerper, rpb-2 antikoerper
    Hintergrund
    POLR2B encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
    Alias Symbols: RPB2, POL2RB, hsRPB2, hRPB140
    Protein Interaction Partner: ESR1, UBC, TCEB3, SRC, PSMB9, SUMO2, XRN2, WWOX, SUZ12, RNF2, NEDD4, ITCH, RABEP2, HECW2, FBXO6, CDK20, HDAC11, ILK, POLR2C, MED19, MED26, RECQL5, VCP, BARD1, MDC1, POLR3F, TUBB4B, TUBA4A, POLR2I, POLR2E, POLR2D, POLR2A, DCTN1, ATP6V1B2, MEN1, CDK7, CCNH,
    Protein Size: 1174
    Molekulargewicht
    134 kDa
    Gen-ID
    5431
    NCBI Accession
    NM_000938, NP_000929
    UniProt
    P30876
    Pathways
    Regulatorische RNA Pathways, DNA Reparatur
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