POLR2B Antikörper (Middle Region)
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- Target Alle POLR2B Antikörper anzeigen
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLR2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- FFRSVFYRSY KEQESKKGFD QEEVFEKPTR ETCQGMRHAI YDKLDDDGLI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against POLR2B. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human POLR2B
- Top Product
- Discover our top product POLR2B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1174 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 609-18, (2008) (PubMed).
: "
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Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 609-18, (2008) (PubMed).
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- Target
- POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))
- Andere Bezeichnung
- POLR2B (POLR2B Produkte)
- Synonyme
- Pol2rb antikoerper, Rpb140 antikoerper, Rpb2 antikoerper, POL2RB antikoerper, RPB2 antikoerper, hRPB140 antikoerper, hsRPB2 antikoerper, RNA polymerase II subunit B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa antikoerper, DNA-directed RNA polymerase II subunit RPB2 antikoerper, polymerase (RNA) II (DNA directed) polypeptide B antikoerper, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog antikoerper, POLR2B antikoerper, polr2b antikoerper, LOC100640211 antikoerper, Polr2b antikoerper, polr2b.L antikoerper, rpb-2 antikoerper
- Hintergrund
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POLR2B encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
Alias Symbols: RPB2, POL2RB, hsRPB2, hRPB140
Protein Interaction Partner: ESR1, UBC, TCEB3, SRC, PSMB9, SUMO2, XRN2, WWOX, SUZ12, RNF2, NEDD4, ITCH, RABEP2, HECW2, FBXO6, CDK20, HDAC11, ILK, POLR2C, MED19, MED26, RECQL5, VCP, BARD1, MDC1, POLR3F, TUBB4B, TUBA4A, POLR2I, POLR2E, POLR2D, POLR2A, DCTN1, ATP6V1B2, MEN1, CDK7, CCNH,
Protein Size: 1174 - Molekulargewicht
- 134 kDa
- Gen-ID
- 5431
- NCBI Accession
- NM_000938, NP_000929
- UniProt
- P30876
- Pathways
- Regulatorische RNA Pathways, DNA Reparatur
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