ID3 Antikörper (N-Term)

Produktnummer ABIN2779573

Produktdetails anti-ID3 Antikörper

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Pferd, Rind (Kuh), Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ID3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKALSPVRGC YEAVCCLSER SLAIARGRGK GPAAEEPLSL LDDMNHCYSR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ID3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ID3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 119 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ID3 Antikörper (ABIN2779573)

Tsuchiya, Okaji, Tsuno, Sakurai, Tsuchiya, Kawai, Yazawa, Asakage, Yamada, Yoneyama, Kitayama, Osada, Watanabe, Tokunaga, Takahashi, Nagawa: "Targeting Id1 and Id3 inhibits peritoneal metastasis of gastric cancer." in: Cancer science, Vol. 96, Issue 11, pp. 784-90, (2005) (PubMed).

Details zu ID3

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Andere Bezeichnung: ID3 (ID3 Produkte)

Synonyme: HEIR-1 antikoerper, bHLHb25 antikoerper, Hlh462 antikoerper, Idb3 antikoerper, fa56g03 antikoerper, tdsubc_2g3 antikoerper, wu:fa56g03 antikoerper, ik:tdsubc_2g3 antikoerper, xx:tdsubc_2g3 antikoerper, XId3 antikoerper, XIdI antikoerper, XIdIa antikoerper, XIdIb antikoerper, XIdx antikoerper, heir-1 antikoerper, id3 antikoerper, xid3 antikoerper, xidia antikoerper, ID3 antikoerper, XIdIIa antikoerper, inhibitor of DNA binding 3, HLH protein antikoerper, inhibitor of DNA binding 3 antikoerper, inhibitor of DNA binding 3, HLH protein L homeolog antikoerper, inhibitor of DNA binding 3, HLH protein S homeolog antikoerper, ID3 antikoerper, Id3 antikoerper, id3 antikoerper, id3.L antikoerper, id3.S antikoerper

Hintergrund: ID3 is a member of the ID family. The members of the family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM].
Alias Symbols: HEIR-1, bHLHb25
Protein Interaction Partner: UBC, TCF12, TCF3, TCF4, FAM74A1, ZNF626, ZNF408, RND1, PUF60, ZNF3, MLX, CNOT3, ID3, GNB2, FHL2, CSK, ATF3, CDK2, SMURF2, PRDM14, CBFA2T2, SAP30, IKBKG, E2F4, GATA4, NKX2-5, ID4, GTF2A1L, ELK4, ELK1, SREBF1, PAX5, MYF6, MYF5, MYOG, MYOD1, IFI16, HES1, RUN
Protein Size: 119

Molekulargewicht: 13 kDa

Gen-ID: 3399

NCBI Accession: NM_002167, NP_002158

UniProt: Q02535