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BMP7 Antikörper (N-Term)

BMP7 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779569
  • Target Alle BMP7 Antikörper anzeigen
    BMP7 (Bone Morphogenetic Protein 7 (BMP7))
    Bindungsspezifität
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 90
    • 43
    • 31
    • 18
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)
    Wirt
    • 84
    • 23
    • 3
    • 1
    Kaninchen
    Klonalität
    • 90
    • 21
    Polyklonal
    Konjugat
    • 56
    • 12
    • 8
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BMP7 Antikörper ist unkonjugiert
    Applikation
    • 88
    • 55
    • 48
    • 17
    • 13
    • 13
    • 12
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QGKHNSAPMF MLDLYNAMAV EEGGGPGGQG FSYPYKAVFS TQGPPLASLQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 91%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 82%
    Produktmerkmale
    This is a rabbit polyclonal antibody against BMP7. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human BMP7
    Top Product
    Discover our top product BMP7 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 431 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Whiteland, Spencer-Harty, Thomas, Davies, Morgan, Kynaston, Bose, Fenn, Lewis, Bodger, Jenkins, Doak: "Putative prognostic epithelial-to-mesenchymal transition biomarkers for aggressive prostate cancer." in: Experimental and molecular pathology, Vol. 95, Issue 2, pp. 220-6, (2013) (PubMed).

    Lovric, Chen, Yu, Oliver, Genin, Walsh: "Effects of demineralized bone matrix on tendon-bone healing in an intra-articular rodent model." in: The American journal of sports medicine, Vol. 40, Issue 10, pp. 2365-74, (2012) (PubMed).

    Rui, Lui, Rolf, Wong, Lee, Chan: "Expression of chondro-osteogenic BMPs in clinical samples of patellar tendinopathy." in: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, Vol. 20, Issue 7, pp. 1409-17, (2012) (PubMed).

    Fiaschetti, Castelletti, Zoller, Schramm, Schroeder, Nagaishi, Stearns, Mittelbronn, Eggert, Westermann, Ohgaki, Shalaby, Pruschy, Arcaro, Grotzer: "Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma." in: Oncogene, Vol. 30, Issue 25, pp. 2823-35, (2011) (PubMed).

    Filion, Li, Mason-Savas, Kreider, Goldstein, Ayers, Song: "Elastomeric osteoconductive synthetic scaffolds with acquired osteoinductivity expedite the repair of critical femoral defects in rats." in: Tissue engineering. Part A, Vol. 17, Issue 3-4, pp. 503-11, (2011) (PubMed).

    Mae, Shirasawa, Yoshie, Sato, Kanoh, Ichikawa, Yokoyama, Yue, Tomotsune, Sasaki: "Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells." in: Biochemical and biophysical research communications, Vol. 393, Issue 4, pp. 877-82, (2010) (PubMed).

    Yi, Tan, Cho, Wang, Luo, Zhang, Li, Liu: "Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17811-20, (2010) (PubMed).

    Morrissey, Brown, Pitts, Vessella, Corey: "Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment." in: Neoplasia (New York, N.Y.), Vol. 12, Issue 2, pp. 192-205, (2010) (PubMed).

  • Target
    BMP7 (Bone Morphogenetic Protein 7 (BMP7))
    Andere Bezeichnung
    BMP7 (BMP7 Produkte)
    Synonyme
    bmp-7 antikoerper, bmp7 antikoerper, op-1 antikoerper, BMP7 antikoerper, zgc:153025 antikoerper, OP-1 antikoerper, OP1 antikoerper, BMP-7 antikoerper, fb83f09 antikoerper, wu:fb83f09 antikoerper, bone morphogenetic protein 7 antikoerper, bone morphogenetic protein 7, gene 1 L homeolog antikoerper, bone morphogenetic protein 7b antikoerper, bone morphogenetic protein 7, gene 2 L homeolog antikoerper, bone morphogenetic protein 7a antikoerper, BMP7 antikoerper, bmp7.1.L antikoerper, LOC100136282 antikoerper, bmp7b antikoerper, Bmp7 antikoerper, LOC100008826 antikoerper, bmp7.2.L antikoerper, bmp7a antikoerper
    Hintergrund
    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
    Alias Symbols: OP-1
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-7, MTUS2, TRIM27, KRTAP5-9, ACTN4, BMPR2, UBC, SMAD3, SOSTDC1, CHRDL2, GDF7, BMPR1B, NOG, ACVR2B, NCOA3, BMPR1A, ENG, ACVR2A, ACVR1, SMAD1, BMP7,
    Protein Size: 431
    Molekulargewicht
    49 kDa
    Gen-ID
    655
    NCBI Accession
    NM_001719, NP_001710
    UniProt
    P18075
    Pathways
    Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
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