WNT2 Antikörper (Middle Region)

Produktnummer ABIN2779467

Produktdetails anti-WNT2 Antikörper

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GSAKDSKGIF DWGGCSDNID YGIKFARAFV DAKERKGKDA RALMNLHNNR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 360 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WNT2

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Andere Bezeichnung: WNT2 (WNT2 Produkte)

Synonyme: CG1916 antikoerper, D-wnt-2 antikoerper, DWnt-2 antikoerper, DWnt2 antikoerper, Dm DWnt2 antikoerper, Dm-2 antikoerper, Dmel\\CG1916 antikoerper, Dwnt-2 antikoerper, Wnt antikoerper, Wnt-2 antikoerper, dWnt2 antikoerper, wnt2 antikoerper, WNT2 antikoerper, irp antikoerper, Xwnt2 antikoerper, wnt-2 antikoerper, Xwnt-2 antikoerper, int1l1 antikoerper, 2610510E18Rik antikoerper, Int1l1 antikoerper, Irp antikoerper, Mirp antikoerper, Wnt2a antikoerper, INT1L1 antikoerper, IRP antikoerper, ZfWnt2 antikoerper, Wnt oncogene analog 2 antikoerper, Wnt family member 2 antikoerper, wingless-type MMTV integration site family member 2 antikoerper, wingless-type MMTV integration site family, member 2 antikoerper, Wnt2 antikoerper, wnt2 antikoerper, WNT2 antikoerper

Hintergrund: WNT2 is the ligand for members of the frizzled family of seven transmembrane receptors. WNT2 is a probable developmental protein. WNT2 may be a signaling molecule which affects the development of discrete regions of tissues. WNT2 is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is expressed in the thalamus. It encodes a protein which shows 96 % amino acid identity to the mouse Wnt2 protein. Based on the map location of this gene in the 7q31 region, and the phenotype of the diminished social interaction in the knockout mouse, this gene is suggested as a strong candidate gene for autism, a prototypical pervasive development disorder. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: INT1L1, IRP
Protein Interaction Partner: RRAGC, UQCR11, HCK, AQP5, SFRP1, WNT3A, FZD1, FZD9,
Protein Size: 360

Molekulargewicht: 38 kDa

Gen-ID: 7472

NCBI Accession: NM_003391, NP_003382

UniProt: P09544

Pathways: WNT Signalweg