WNT2 Antikörper (Wingless-Type MMTV Integration Site Family Member 2) (Middle Region)

Details for Product anti-WNT2 Antibody No. ABIN2779467, Anbieter: Anmelden zum Anzeigen
Antigen
  • CG1916
  • D-wnt-2
  • DWnt-2
  • DWnt2
  • Dm DWnt2
  • Dm-2
  • Dmel\\CG1916
  • Dwnt-2
  • Wnt
  • Wnt-2
  • dWnt2
  • wnt2
  • WNT2
  • irp
  • Xwnt2
  • wnt-2
  • Xwnt-2
  • int1l1
  • 2610510E18Rik
  • Int1l1
  • Irp
  • Mirp
  • Wnt2a
  • INT1L1
  • IRP
  • ZfWnt2
  • Wnt oncogene analog 2
  • wingless-type MMTV integration site family member 2
  • wingless-related MMTV integration site 2
  • Wnt2
  • wnt2
  • LOC100221216
  • WNT2
Epitop
Middle Region
15
6
3
3
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Schaf, Zebrafisch
65
38
31
18
4
3
3
3
3
3
2
2
2
Wirt
Kaninchen
67
Klonalität
Polyklonal
Konjugat
Dieser WNT2 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
41
14
13
11
5
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human WNT2
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN986213.
Sequenz GSAKDSKGIF DWGGCSDNID YGIKFARAFV DAKERKGKDA RALMNLHNNR
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 87%
Produktmerkmale This is a rabbit polyclonal antibody against WNT2. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung WNT2 (WNT2 Antibody Abstract)
Hintergrund WNT2 is the ligand for members of the frizzled family of seven transmembrane receptors. WNT2 is a probable developmental protein. WNT2 may be a signaling molecule which affects the development of discrete regions of tissues. WNT2 is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is expressed in the thalamus. It encodes a protein which shows 96 % amino acid identity to the mouse Wnt2 protein. Based on the map location of this gene in the 7q31 region, and the phenotype of the diminished social interaction in the knockout mouse, this gene is suggested as a strong candidate gene for autism, a prototypical pervasive development disorder. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: INT1L1, IRP
Protein Interaction Partner: RRAGC, UQCR11, HCK, AQP5, SFRP1, WNT3A, FZD1, FZD9,
Protein Size: 360
Molekulargewicht 38 kDa
Gen-ID 7472
NCBI Accession NM_003391, NP_003382
UniProt P09544
Forschungsgebiet Cancer, Wnt
Pathways WNT Signalweg
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 360 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family Member 2 (WNT2) (Middle Region) antibody (ABIN2779467) WB Suggested Anti-WNT2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Allgemeine Veröffentlichungen Han, Zhang, Chen, Jiang, Kong, Sun, Wu, Huang, Li, Liu: "Expression of seven gastric cancer-associated genes and its relevance for Wnt, NF-kappaB and Stat3 signaling." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 115, Issue 12, pp. 1331-43, 2008 (PubMed).

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