Serotonin Receptor 2B Antikörper (HTR2B) (N-Term)

Details for Product anti-HTR2B Antibody No. ABIN2779377, Anbieter: Anmelden zum Anzeigen
Antigen
  • 5-HT2B
  • 5HT2B
  • 5htr2b
  • HTR2B
  • 5ht2b
  • zgc:194094
  • zgc:194119
  • AJ012488
  • AV377389
  • 5-HT(2B)
  • 5-hydroxytryptamine (serotonin) receptor 2B
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • HTR2B
  • htr2b
  • LOC100228803
  • Htr2b
Epitop
N-Term
13
11
7
6
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Schwein
117
44
36
3
1
1
1
1
1
Wirt
Kaninchen
114
11
Klonalität
Polyklonal
Konjugat
Dieser Serotonin Receptor 2B Antikörper ist unkonjugiert
5
5
5
3
3
3
3
3
3
3
3
2
2
2
2
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
66
34
33
32
28
18
5
3
2
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2B
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN978347.
Sequenz QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
Homologie Cow: 100%, Dog: 80%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 87%
Produktmerkmale This is a rabbit polyclonal antibody against HTR2B. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung HTR2B (HTR2B Antibody Abstract)
Hintergrund Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alias Symbols: 5-HT(2B), 5-HT2B
Protein Interaction Partner: AGTR1, SNTA1, LNX1, GNAQ, GNA11,
Protein Size: 481
Molekulargewicht 54 kDa
Gen-ID 3357
NCBI Accession NM_000867, NP_000858
UniProt P41595
Pathways JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 481 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibody (ABIN2779377) WB Suggested Anti-HTR2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibody (ABIN2779377) Host: Rabbit
Target Name: HTR2B
Sample Tissue: Human Adult Placenta
Western Blotting (WB) image for anti-Serotonin Receptor 2B (HTR2B) (N-Term) antibody (ABIN2779377) Host: Rabbit
Target Name: HTR2B
Sample Tissue: Human Fetal Lung
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