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OAS1 Antikörper (C-Term)

OAS1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779349
  • Target Alle OAS1 Antikörper anzeigen
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    Bindungsspezifität
    • 11
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 62
    • 36
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 60
    • 3
    • 1
    Kaninchen
    Klonalität
    • 61
    • 3
    Polyklonal
    Konjugat
    • 29
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser OAS1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 28
    • 23
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    EAWLNYPCFK NWDGSPVSSW ILLAESNSAD DETDDPRRYQ KYGYIGTHEY
    Homologie
    Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against OAS1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product OAS1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 400 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Tainsky: "Higher miRNA tolerance in immortal Li-Fraumeni fibroblasts with abrogated interferon signaling pathway." in: Cancer research, Vol. 71, Issue 1, pp. 255-65, (2011) (PubMed).

  • Target
    OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
    Andere Bezeichnung
    OAS1 (OAS1 Produkte)
    Synonyme
    OAS1 antikoerper, IFI-4 antikoerper, OIAS antikoerper, OIASI antikoerper, L3 antikoerper, Pp2a2 antikoerper, 2',5'-oligoadenylate synthetase 1 antikoerper, 2'-5'-oligoadenylate synthetase 1 antikoerper, 2'-5' oligoadenylate synthetase 1A antikoerper, protein phosphatase 2 catalytic subunit beta antikoerper, OAS1 antikoerper, Oas1a antikoerper, Ppp2cb antikoerper, Oas1 antikoerper
    Hintergrund
    OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.
    Alias Symbols: IFI-4, OIAS, OIASI
    Protein Interaction Partner: EXOC5, TRIM27, ACTN1, PRMT6, WBSCR22, RPL30, HCVgp1,
    Protein Size: 400
    Molekulargewicht
    46 kDa
    Gen-ID
    4938
    NCBI Accession
    NM_016816, NP_058132
    UniProt
    P00973
    Pathways
    Hepatitis C
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