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RGS4 Antikörper (C-Term)

RGS4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Hund, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779301
  • Target Alle RGS4 Antikörper anzeigen
    RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
    Bindungsspezifität
    • 7
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Hund, Pferd
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RGS4 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 15
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL
    Homologie
    Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RGS4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human RGS4
    Top Product
    Discover our top product RGS4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 205 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
    Andere Bezeichnung
    RGS4 (RGS4 Produkte)
    Synonyme
    RGP4 antikoerper, SCZD9 antikoerper, AA004315 antikoerper, AA597169 antikoerper, ESTM48 antikoerper, ESTM50 antikoerper, regulator of G protein signaling 4 antikoerper, regulator of G-protein signaling 4 antikoerper, RGS4 antikoerper, Rgs4 antikoerper
    Hintergrund
    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.
    Alias Symbols: MGC2124, MGC60244, RGP4, SCZD9
    Protein Interaction Partner: GABBR1, KRIT1, PLCB1, COPB2, GNAQ, COPB1, ERBB3, PTAFR, GNAI2, GNAO1, GNAI1, CALM1, GNAI3, GNAT1,
    Protein Size: 205
    Molekulargewicht
    23 kDa
    Gen-ID
    5999
    NCBI Accession
    NM_005613, NP_005604
    UniProt
    P49798
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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