RNP Antikörper (Middle Region)

Produktnummer ABIN2779114

Produktdetails anti-RNP Antikörper

Target: RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LHAPLPPTSP QPPEEPPLPD EDEELSSEES EYESTDDEDR QRMNKLMELA

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 92%, Rat: 85%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against RNPC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNPC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 517 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNP

Target: RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))

Andere Bezeichnung: RNPC3 (RNPC3 Produkte)

Synonyme: rnp antikoerper, rbm40 antikoerper, zgc:136847 antikoerper, RBM40 antikoerper, RNP antikoerper, SNRNP65 antikoerper, 2810441O16Rik antikoerper, AI447568 antikoerper, C030014B17Rik antikoerper, RNA binding region (RNP1, RRM) containing 3 antikoerper, RNA-binding region (RNP1, RRM) containing 3 antikoerper, RNPC3 antikoerper, rnpc3 antikoerper, Rnpc3 antikoerper

Hintergrund: RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
Protein Interaction Partner: SMAD2, CPSF1, CDK19, RPS3A, APP, PRNP, RNU11, RNU12-2P,
Protein Size: 517

Molekulargewicht: 58 kDa

Gen-ID: 55599

NCBI Accession: NM_017619, NP_060089

UniProt: Q96LT9