RBM14 Antikörper (N-Term)

Produktnummer ABIN2778973

Produktdetails anti-RBM14 Antikörper

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YAFVHMEKEA DAKAAIAQLN GKEVKGKRIN VELSTKGQKK GPGLAVQSGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBM14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 669 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RBM14 Antikörper (ABIN2778973)

Sui, Yang, Xiong, Zhang, Blanchard, Peiper, Dynan, Tuan, Ko: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." in: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).

Details zu RBM14

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Andere Bezeichnung: RBM14 (RBM14 Produkte)

Synonyme: im:7053198 antikoerper, wu:fc08a04 antikoerper, zgc:110682 antikoerper, sip antikoerper, coaa antikoerper, psp2 antikoerper, sytip1 antikoerper, tmem137 antikoerper, MGC52864 antikoerper, MGC132117 antikoerper, MGC75876 antikoerper, RBM14 antikoerper, RBM4 antikoerper, COAA antikoerper, PSP2 antikoerper, SIP antikoerper, SYTIP1 antikoerper, TMEM137 antikoerper, 1300007E16Rik antikoerper, Sytip antikoerper, p16 antikoerper, p16K antikoerper, CoAA antikoerper, rbm14 antikoerper, zgc:85696 antikoerper, RNA binding motif protein 14a antikoerper, RNA binding motif protein 14 L homeolog antikoerper, RNA binding motif protein 14 antikoerper, RNA binding motif protein 14b antikoerper, rbm14a antikoerper, rbm14.L antikoerper, rbm14 antikoerper, RBM14 antikoerper, Rbm14 antikoerper, rbm14b antikoerper

Hintergrund: RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
Alias Symbols: COAA, DKFZp779J0927, SIP, SYTIP1, PSP2, TMEM137
Protein Interaction Partner: UBC, SUMO2, SUMO3, CEP250, DROSHA, MDM2, SMURF2, RPA3, RPA2, RPA1, EZH2, BMI1, RNF2, SUZ12, EED, MAPK15, CDK15, CDK14, HDAC9, HDAC11, WHSC1, VCAM1, TRAF3, ITGA4, FN1, ESR1, ZC3H18, FTSJ3, RBM25, TRMT112, HP1BP3, PRPF19, RBMX, RSL1D1, PRPF6, HNRNPH1, RCC1,
Protein Size: 669

Molekulargewicht: 69 kDa

Gen-ID: 10432

NCBI Accession: NM_006328, NP_006319

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway