AGFG1 Antikörper (Middle Region)

Produktnummer ABIN2778893

Produktdetails anti-AGFG1 Antikörper

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGFG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SQSPVVGRSQ GQQQEKKQFD LLSDLGSDIF AAPAPQSTAT ANFANFAHFN

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HRB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HRB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 562 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Andere Bezeichnung: HRB (HRB Produkte)

Hintergrund: HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. HRB binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs.The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. This encoded protein binds the Rev activation domain when Rev is assembled onto its RNA target and can significantly enhance Rev activity when overexpressed. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC116938, MGC116940, RAB, RIP, HRB
Protein Interaction Partner: NYAP2, POLE2, UBC, ALAD, P3H1, NIF3L1, PPME1, IPO11, SH3GLB1, LAP3, TPRKB, DBNL, HSPBP1, GPN1, ARPC1A, ZPR1, OGT, SURF2, LPP, VCAM1, ITGA4, SUCLA2, APP, EPS15, vpr, ITSN1, APC, RNF216, EPS15L1, PKIA, XPO1, AGFG1, VAMP7, CRM1, KAP104,
Protein Size: 562

Molekulargewicht: 58 kDa

Gen-ID: 3267

NCBI Accession: NM_004504, NP_004495

UniProt: P52594