PRKRA Antikörper (Middle Region)

Produktnummer ABIN2778859

Produktdetails anti-PRKRA Antikörper

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA KRNAAEKFLA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRKRA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRKRA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 313 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRKRA Antikörper (ABIN2778859)

Yoshida, Okamura, Hoshino, Shono, Yoshioka, Hinode, Yoshida: "Interaction between PKR and PACT mediated by LPS-inducible NF-?B in human gingival cells." in: Journal of cellular biochemistry, Vol. 113, Issue 1, pp. 165-73, (2011) (PubMed).

Details zu PRKRA

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Andere Bezeichnung: PRKRA (PRKRA Produkte)

Synonyme: PRKRA antikoerper, AV120107 antikoerper, PRK antikoerper, Pact antikoerper, RAX antikoerper, lear antikoerper, DYT16 antikoerper, PACT antikoerper, im:7151758 antikoerper, zgc:162619 antikoerper, dyt16 antikoerper, pact antikoerper, prkra-a antikoerper, prkra-b antikoerper, rax antikoerper, rbpa antikoerper, protein activator of interferon induced protein kinase EIF2AK2 antikoerper, protein kinase, interferon inducible double stranded RNA dependent activator antikoerper, protein kinase, interferon-inducible double stranded RNA dependent activator antikoerper, protein activator of interferon induced protein kinase EIF2AK2 L homeolog antikoerper, PRKRA antikoerper, Prkra antikoerper, prkra antikoerper, prkra.L antikoerper

Hintergrund: PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).
Alias Symbols: RAX, PACT, DYT16, HSD14
Protein Interaction Partner: ZMAT3, PRKRA, TARBP2, LYAR, STAU1, UBC, H1F0, EIF2AK2, CCDC124, C1orf35, DDX50, NOC3L, NOP16, STAU2, ZNF346, GTPBP4, DICER1, RBM34, EBNA1BP2, IFRD2, TCOF1, BMI1, SRPK3, POLR2G, MDC1, CAND1, UBE2I, SIRT7, ZFP28, KIAA1377, NKRF, SNX5, RABEPK, CEBPZ, SHC1, Z
Protein Size: 313

Molekulargewicht: 34 kDa

Gen-ID: 8575

NCBI Accession: NM_003690, NP_003681

UniProt: O75569

Pathways: Regulatorische RNA Pathways