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HNRNPL Antikörper (N-Term)

HNRNPL Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778695
  • Target Alle HNRNPL Antikörper anzeigen
    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
    Bindungsspezifität
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 52
    • 24
    • 10
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 47
    • 6
    Kaninchen
    Klonalität
    • 49
    • 4
    Polyklonal
    Konjugat
    • 35
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser HNRNPL Antikörper ist unkonjugiert
    Applikation
    • 35
    • 19
    • 17
    • 15
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    DTWDYTNPNL SGQGDPGSNP NKRQRQPPLL GDHPAEYGGP HGGYHSHYHD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
    Produktmerkmale
    This is a rabbit polyclonal antibody against HNRPL. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPL
    Top Product
    Discover our top product HNRNPL Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 589 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
    Andere Bezeichnung
    HNRPL (HNRNPL Produkte)
    Synonyme
    HNRPL antikoerper, hnRNP-L antikoerper, zgc:55429 antikoerper, HNRNPL antikoerper, hnrpl antikoerper, C79783 antikoerper, D830027H13Rik antikoerper, Hnrpl antikoerper, hnrnp-L antikoerper, heterogeneous nuclear ribonucleoprotein L antikoerper, HNRNPL antikoerper, hnrpl antikoerper, hnrnpl antikoerper, Hnrnpl antikoerper
    Hintergrund
    Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: P/OKcl.14, hnRNP-L, HNRPL
    Protein Interaction Partner: TP53, FUS, TRIM68, SUMO2, SUMO3, IVNS1ABP, UBC, MDM2, RPA3, RPA2, RPA1, ILF3, HNRNPA2B1, EED, VHL, VEGFA, RNF2, NEDD4, ITCH, FBXO6, HMGA1, vif, TP63, UBL4A, WHSC1, VCAM1, ITGA4, IL7R, IFIT3, IFIT2, FN1, DAB2, CSNK2A1, EIF4A3, MAGOH, HNRNPA3, NPLOC4, LSM14
    Protein Size: 589
    Molekulargewicht
    65 kDa
    Gen-ID
    3191
    NCBI Accession
    NM_001533, NP_001524
    UniProt
    P14866
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