RNF8 Antikörper (C-Term)

Produktnummer ABIN2778597

Produktdetails anti-RNF8 Antikörper

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 485 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Andere Bezeichnung: RNF8 (RNF8 Produkte)

Synonyme: hRNF8 antikoerper, 3830404E21Rik antikoerper, AIP37 antikoerper, RNF8 antikoerper, rnf8 antikoerper, fc66f09 antikoerper, wu:fc66f09 antikoerper, zgc:55936 antikoerper, zgc:77313 antikoerper, ring finger protein 8 antikoerper, ring finger protein 8, E3 ubiquitin protein ligase S homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase L homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase antikoerper, RNF8 antikoerper, Rnf8 antikoerper, rnf8.S antikoerper, rnf8.L antikoerper, rnf8 antikoerper

Hintergrund: RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ12013, KIAA0646
Protein Interaction Partner: TMEM79, HOMEZ, SEPT3, RBFOX2, PNMA2, USP16, WASL, HERC2, MAD1L1, VCP, TNFRSF1A, TNF, BCL10, UBE2N, UBC, NEDD8, JMJD1C, MDC1, EXOSC2, MDM2, BLM, SEPT8, SEPT7, RPSA, H2AFX, RL2, HIST2H2BE, HIST2H2AC, PCNA, RAD50, NBN, MRE11A, UBE2E3, UBE2V1, UBE2E2, UBE2E1,
Protein Size: 485

Molekulargewicht: 55 kDa

Gen-ID: 9025

NCBI Accession: NM_003958, NP_003949

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response