MED17 Antikörper (Mediator Complex Subunit 17) (N-Term)

Details for Product anti-MED17 Antibody No. ABIN2778320, Anbieter: Anmelden zum Anzeigen
Antigen
  • crsp6
  • CRSP6
  • CRSP77
  • DRIP80
  • TRAP80
  • 77kDa
  • C330002H14Rik
  • Crsp6
  • Trap80
  • mediator of RNA polymerase II transcription subunit 17
  • mediator complex subunit 17
  • mediator complex subunit 17 L homeolog
  • AOR_1_2446154
  • VDBG_01663
  • med17
  • med17.L
  • MED17
  • Med17
Epitop
N-Term
15
10
9
8
4
4
3
2
2
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
79
29
21
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
60
19
Klonalität
Polyklonal
Konjugat
Dieser MED17 Antikörper ist unkonjugiert
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
61
36
13
12
12
9
8
3
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975330.
Sequenz AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
Reinigung Affinity Purified
Andere Bezeichnung CRSP6 (MED17 Antibody Abstract)
Hintergrund The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651
Molekulargewicht 73 kDa
Gen-ID 9440
NCBI Accession NM_004268, NP_004259
UniProt Q9NVC6
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 651 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (ABIN2778320) WB Suggested Anti-CRSP6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (ABIN2778320) anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (Image 2)
Chromatin Immunoprecipitation (ChIP) image for anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (ABIN2778320) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (ABIN2778320) Rabbit Anti-MED17 Antibody ,Paraffin Embedded Tissue: Human neural cell
Cellul...
Allgemeine Veröffentlichungen Wang, Sharma, Ren, Fondell: "A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 42852-8, 2002 (PubMed).

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