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TRIM21 Antikörper (N-Term)

TRIM21 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778305
  • Target Alle TRIM21 Antikörper anzeigen
    TRIM21 (Tripartite Motif Containing 21 (TRIM21))
    Bindungsspezifität
    • 15
    • 10
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 55
    • 27
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Meerschweinchen, Hund, Kaninchen
    Wirt
    • 49
    • 8
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 54
    • 7
    Polyklonal
    Konjugat
    • 39
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIM21 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 22
    • 13
    • 13
    • 12
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GELRRKQELA EKLEVEIAIK RADWKKTVET QKSRIHAEFV QQKNFLVEEE
    Homologie
    Dog: 77%, Guinea Pig: 92%, Human: 100%, Mouse: 83%, Rabbit: 85%, Rat: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TRIM21. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM21
    Top Product
    Discover our top product TRIM21 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 475 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TRIM21 (Tripartite Motif Containing 21 (TRIM21))
    Andere Bezeichnung
    TRIM21 (TRIM21 Produkte)
    Synonyme
    RNF81 antikoerper, RO52 antikoerper, SSA antikoerper, SSA1 antikoerper, Ro52 antikoerper, Ssa1 antikoerper, tripartite motif containing 21 antikoerper, tripartite motif-containing 21 antikoerper, TRIM21 antikoerper, Trim21 antikoerper
    Hintergrund
    TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RNF81, RO52, SSA, SSA1
    Protein Interaction Partner: TRIM39, IGHV4-31, TXN2, GRAP, UBE2I, TRIM21, IGHG1, USP15, HAUS2, UBE2D2, UBC, FBXO6, UBD, NPM1, PAN2, ROR1, NOS2, MYC, IQCB1, USP2, VCP, USP4, CDC34, CBL, UBC4, UBE2C, UBE2L3, UBE2H, UBE2D1, TROVE2, TRIM27, MNAT1, FCGR2A, CD52, DCP2, ZFPM1, TRIM5, TRIM8,
    Protein Size: 475
    Molekulargewicht
    54 kDa
    Gen-ID
    6737
    NCBI Accession
    NM_003141, NP_003132
    UniProt
    P19474
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