Tryptophan Hydroxylase 2 Antikörper (N-Term)

Produktnummer ABIN2778285

Produktdetails anti-Tryptophan Hydroxylase 2 Antikörper

Target: Tryptophan Hydroxylase 2 (TPH2)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tryptophan Hydroxylase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: REAATESGKT AVVFSLKNEV GGLVKALRLF QEKRVNMVHI ESRKSRRRSS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against TPH2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 490 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Tryptophan Hydroxylase 2 Antikörper (ABIN2778285)

Walther, Peter, Bashammakh, Hörtnagl, Voits, Fink, Bader: "Synthesis of serotonin by a second tryptophan hydroxylase isoform." in: Science (New York, N.Y.), Vol. 299, Issue 5603, pp. 76, (2003) (PubMed).

Details zu Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Andere Bezeichnung: TPH2 (TPH2 Produkte)

Synonyme: ADHD7 antikoerper, NTPH antikoerper, Ntph antikoerper, tphR antikoerper, wu:fq15a04 antikoerper, AU043594 antikoerper, tryptophan hydroxylase 2 antikoerper, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) antikoerper, TPH2 antikoerper, Tph2 antikoerper, tph2 antikoerper

Hintergrund: Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
Alias Symbols: NTPH, ADHD7
Protein Interaction Partner: UBC,
Protein Size: 490

Molekulargewicht: 56 kDa

Gen-ID: 121278

NCBI Accession: NM_173353, NP_775489

UniProt: Q8IWU9