PTGER3 Antikörper (Middle Region)
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- Target Alle PTGER3 Antikörper anzeigen
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PTGER3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ILDPWVYLLL RKILLRKFCQ IRYHTNNYAS SSTSLPCQCS STLMWSDHLE
- Homologie
- Horse: 100%, Human: 100%, Rabbit: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PTGER3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PTGER3
- Top Product
- Discover our top product PTGER3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 390 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
- Andere Bezeichnung
- PTGER3 (PTGER3 Produkte)
- Synonyme
- PTGER3 antikoerper, EP3 antikoerper, EP3-I antikoerper, EP3-II antikoerper, EP3-III antikoerper, EP3-IV antikoerper, EP3e antikoerper, PGE2-R antikoerper, PTGEREP3 antikoerper, Rep3 antikoerper, rEP3a antikoerper, rEP3b antikoerper, Pgerep3 antikoerper, Ptgerep3 antikoerper, prostaglandin E receptor 3 antikoerper, prostaglandin E receptor 3 L homeolog antikoerper, prostaglandin E receptor 3 (subtype EP3) antikoerper, PTGER3 antikoerper, ptger3.L antikoerper, Ptger3 antikoerper
- Hintergrund
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PTGER3 is the receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Alias Symbols: EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302, PGE2-R
Protein Interaction Partner: NOTCH2NL, INCA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, TRIM42, MGAT5B, KRT40, CCDC33, ADAMTSL4, EFEMP2, RGS17, SPRY2, KRT38, RGS20, TCF4, REL, MEOX2, KRT31, CDA, GHRL, MKLN1, PTGER1,
Protein Size: 390 - Molekulargewicht
- 43 kDa
- Gen-ID
- 5733
- NCBI Accession
- NM_198719, NP_942012
- UniProt
- P43115
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