WNT8B Antikörper (Middle Region)

Produktnummer ABIN2777967

Produktdetails anti-WNT8B Antikörper

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Zebrafisch (Danio rerio), Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KCHGVSGSCT TQTCWLQLPE FREVGAHLKE KYHAALKVDL LQGAGNSAAG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT8B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT8B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 351 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WNT8B

Target: WNT8B (Wingless-Type MMTV Integration Site Family, Member 8B (WNT8B))

Andere Bezeichnung: WNT8B (WNT8B Produkte)

Synonyme: WNT8B antikoerper, wnt-8b antikoerper, xwnt-8b antikoerper, xwnt8b antikoerper, Wnt family member 8B antikoerper, protein Wnt-8b antikoerper, wingless-type MMTV integration site family, member 8B antikoerper, wingless-type MMTV integration site family, member 8b antikoerper, Wnt family member 8B S homeolog antikoerper, WNT8B antikoerper, LOC100079874 antikoerper, Wnt8b antikoerper, wnt8b antikoerper, wnt8b.S antikoerper

Hintergrund: The WNT family consists of sereval secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT8B is a protein which shows 95 % , 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95 %, 86 % and 71 % amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.
Protein Size: 351

Molekulargewicht: 39 kDa

Gen-ID: 7479

NCBI Accession: NM_003393, NP_003384

UniProt: Q93098

Pathways: WNT Signalweg