DMAP1 Antikörper (N-Term)

Produktnummer ABIN2777663

Produktdetails anti-DMAP1 Antikörper

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DAWTKAETDH LFDLSRRFDL RFVVIHDRYD HQQFKKRSVE DLKERYYHIC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 467 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DMAP1

Target: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Andere Bezeichnung: DMAP1 (DMAP1 Produkte)

Synonyme: Afu4g07380 antikoerper, T8I13.5 antikoerper, DNMAP1 antikoerper, DNMTAP1 antikoerper, EAF2 antikoerper, MEAF2 antikoerper, SWC4 antikoerper, zgc:55593 antikoerper, dnmap1 antikoerper, dnmtap1 antikoerper, eaf2 antikoerper, meaf2 antikoerper, swc4 antikoerper, 1500016M21Rik antikoerper, Dmtap1 antikoerper, mKIAA1425 antikoerper, DNA methyltransferase 1-associated protein DMAP1 antikoerper, DNA methyltransferase 1-associated protein 1 antikoerper, DNA methyltransferase 1 associated protein 1 antikoerper, myb-like transcription factor family protein antikoerper, DNA methyltransferase 1 associated protein 1 L homeolog antikoerper, AFUA_4G07380 antikoerper, NFIA_108840 antikoerper, ACLA_046700 antikoerper, CpipJ_CPIJ017959 antikoerper, Bm1_47540 antikoerper, PMAA_026820 antikoerper, AFLA_112450 antikoerper, TSTA_072020 antikoerper, BDBG_02603 antikoerper, AT2G47210 antikoerper, CpipJ_CPIJ007438 antikoerper, DMAP1 antikoerper, dmap1 antikoerper, dmap1.L antikoerper, Dmap1 antikoerper

Hintergrund: DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
Protein Interaction Partner: SOX2, UBC, RNF2, HECW2, RUVBL2, SRCAP, CFDP1, RUVBL1, DENR, VPS72, TOMM34, TSG101, H2AFZ, DAXX, SMARCAD1, SUMO2, EPC1, ACTL6A, ACTA1, PPP2R2D, ING3, MORF4L1, BRD8, KAT5, TRRAP, YEATS4, EP400, EPC2, MYC, MAX, ACTG1, ACTB, MRGBP, MORF4L2, MNAT1, HDAC1, tat,
Protein Size: 467

Molekulargewicht: 51 kDa

Gen-ID: 55929

NCBI Accession: NM_001034024, NP_001029196

UniProt: Q9NPF5