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PCK1 Antikörper (Middle Region)

PCK1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Schwein, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777602
  • Target Alle PCK1 Antikörper anzeigen
    PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
    Bindungsspezifität
    • 15
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 77
    • 53
    • 28
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Schwein, Meerschweinchen
    Wirt
    • 91
    • 9
    • 2
    • 2
    Kaninchen
    Klonalität
    • 88
    • 16
    Polyklonal
    Konjugat
    • 46
    • 10
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser PCK1 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 43
    • 32
    • 18
    • 14
    • 13
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    NGFFGVAPGT SVKTNPNAIK TIQKNTIFTN VAETSDGGVY WEGIDEPLAS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PCK1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PCK1
    Top Product
    Discover our top product PCK1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 622 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Perrone, Mattocks, Plummer, Chittur, Mohney, Vignola, Orentreich, Orentreich: "Genomic and metabolic responses to methionine-restricted and methionine-restricted, cysteine-supplemented diets in Fischer 344 rat inguinal adipose tissue, liver and quadriceps muscle." in: Journal of nutrigenetics and nutrigenomics, Vol. 5, Issue 3, pp. 132-57, (2012) (PubMed).

  • Target
    PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
    Andere Bezeichnung
    PCK1 (PCK1 Produkte)
    Synonyme
    PEPCK-C antikoerper, PEPCK1 antikoerper, PEPCKC antikoerper, PEPCK antikoerper, PEPCK-M antikoerper, PEPCK2 antikoerper, 1810010O14Rik antikoerper, 9130022B02Rik antikoerper, cb856 antikoerper, cb924 antikoerper, fj93h11 antikoerper, zgc:63869 antikoerper, wu:fc51c05 antikoerper, wu:fj93h11 antikoerper, pepck-c antikoerper, pepck1 antikoerper, pepckc antikoerper, PCK1 antikoerper, PPCK1 antikoerper, AI265463 antikoerper, Pck-1 antikoerper, GTP antikoerper, PCK antikoerper, Pepck antikoerper, RATPEPCK antikoerper, Ppc1C antikoerper, PHOSPHOENOLPYRUVATE CARBOXYKINASE antikoerper, T28I19.150 antikoerper, T28I19_150 antikoerper, phosphoenolpyruvate carboxykinase 1 antikoerper, 143299_at antikoerper, CG10924 antikoerper, CG17725 antikoerper, Dmel\\CG17725 antikoerper, Dromel_CG17725_FBtr0086701_pepck_mORF antikoerper, dPEPCK antikoerper, pepck antikoerper, PEPC antikoerper, PEPCase antikoerper, ppc antikoerper, phosphoenolpyruvate carboxykinase 1 antikoerper, phosphoenolpyruvate carboxykinase 2, mitochondrial antikoerper, phosphoenolpyruvate carboxykinase 2 (mitochondrial) antikoerper, phosphoenolpyruvate carboxykinase 1 (soluble) antikoerper, phosphoenolpyruvate carboxykinase 1 S homeolog antikoerper, phosphoenolpyruvate carboxykinase, cytosolic [GTP] antikoerper, phosphoenolpyruvate carboxykinase 1, cytosolic antikoerper, phosphoenolpyruvate carboxylase 7 antikoerper, Phosphoenolpyruvate carboxykinase antikoerper, phosphoenolpyruvate carboxylase antikoerper, PCK1 antikoerper, PCK2 antikoerper, Pck2 antikoerper, pck1 antikoerper, pck1.S antikoerper, LOC100634531 antikoerper, Pck1 antikoerper, pep7 antikoerper, Pepck antikoerper, LOC107777405 antikoerper
    Hintergrund
    PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet.This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC22652, PEPCK-C, PEPCK1, PEPCKC
    Protein Interaction Partner: UBC, FBXO25, C1R, APP, CUL5, BAG6, TCP1, TCEB1, SKP1, RPS15A, RPS6, RPS3A, RPS3, RPLP0, RPL4, PSMD12, PSMD2, PSMC5, PSMC4, PSMC2, PSMC1, PSMB7, PSMB4, PSMB1, PSMA5, PSMA2, PCK1, LDHA, HSPD1, HSPA1L, DNAJA1, HLA-C, HLA-B, GNAS, GNAI1, GNA12, FASN, EP300, T
    Protein Size: 622
    Molekulargewicht
    69 kDa
    Gen-ID
    5105
    NCBI Accession
    NM_002591, NP_002582
    UniProt
    P35558
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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