OLIG2 Antikörper (C-Term)

Produktnummer ABIN2777566

Produktdetails anti-OLIG2 Antikörper

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AAVSSASLPG SGLPSVGSIR PPHGLLKSPS AAAAAPLGGG GGGSGASGGF

Homologie: Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against OLIG2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human OLIG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 323 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-OLIG2 Antikörper (ABIN2777566)

Sun, Hafler, Kaing, Kitada, Ligon, Widlund, Yuk, Stiles, Rowitch: "Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube." in: Developmental biology, Vol. 292, Issue 1, pp. 152-64, (2006) (PubMed).

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: OLIG2 (OLIG2 Produkte)

Synonyme: olig3.2 antikoerper, MGC89336 antikoerper, OLIG2 antikoerper, BHLHB1 antikoerper, OLIGO2 antikoerper, PRKCBP2 antikoerper, RACK17 antikoerper, bHLHe19 antikoerper, wu:fc64g09 antikoerper, AI604895 antikoerper, Bhlhb1 antikoerper, Olg-2 antikoerper, Oligo2 antikoerper, RK17 antikoerper, oligodendrocyte transcription factor 4 antikoerper, oligodendrocyte transcription factor 2 antikoerper, oligodendrocyte lineage transcription factor 2 antikoerper, olig4 antikoerper, OLIG2 antikoerper, Olig2 antikoerper, olig2 antikoerper

Hintergrund: OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14,21)(q11.2,q22). OLIG2 might play a role in learning deficits associated with Down syndrome.
Alias Symbols: BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Protein Interaction Partner: CUL3, SRRM1, SOX8, NKX2-2, EP300, SOX10,
Protein Size: 323

Molekulargewicht: 32 kDa

Gen-ID: 10215

NCBI Accession: NM_005806, NP_005797

UniProt: Q13516