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DREAM Antikörper (N-Term)

KCNIP3 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777506
  • Target Alle DREAM (KCNIP3) Antikörper anzeigen
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 55
    • 31
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schwein
    Wirt
    • 48
    • 6
    • 2
    Kaninchen
    Klonalität
    • 53
    • 3
    Polyklonal
    Konjugat
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DREAM Antikörper ist unkonjugiert
    Applikation
    • 51
    • 26
    • 21
    • 13
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    STVRHQPEGL DQLQAQTKFT KKELQSLYRG FKNECPTGLV DEDTFKLIYA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CSEN. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CSEN
    Top Product
    Discover our top product KCNIP3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 256 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." in: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

  • Target
    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
    Andere Bezeichnung
    CSEN (KCNIP3 Produkte)
    Synonyme
    CSEN antikoerper, DREAM antikoerper, KCHIP3 antikoerper, 4933407H12Rik antikoerper, AI413860 antikoerper, Csen antikoerper, KChIP3 antikoerper, R74849 antikoerper, Dream antikoerper, rKChIP3 antikoerper, csen antikoerper, im:7145308 antikoerper, kcnip3 antikoerper, zgc:73306 antikoerper, KCNIP3 antikoerper, potassium voltage-gated channel interacting protein 3 antikoerper, Kv channel-interacting protein 4 antikoerper, calsenilin antikoerper, Kv channel interacting protein 3, calsenilin antikoerper, Kv channel interacting protein 3b, calsenilin antikoerper, KCNIP3 antikoerper, LOC5568664 antikoerper, CpipJ_CPIJ002549 antikoerper, Tsp_05009 antikoerper, Kcnip3 antikoerper, kcnip3b antikoerper, kcnip3 antikoerper
    Hintergrund
    CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
    Alias Symbols: CSEN, DREAM, KCHIP3
    Protein Interaction Partner: MAVS, CD177, IGLV3-25, IL6ST, IGF1R, KCND2, CLN3, CALM2, KCNIP3, PPP3CA, GRK6, ADRBK1, UBE2I, UBC, PCBD2, TARBP2, PSEN2, CASP3, CREM, CREB1, PSEN1, CRK,
    Protein Size: 256
    Molekulargewicht
    29 kDa
    Gen-ID
    30818
    NCBI Accession
    NM_013434, NP_038462
    UniProt
    Q9Y2W7
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