PDK2 Antikörper (Middle Region)

Produktnummer ABIN2777433

Produktdetails anti-PDK2 Antikörper

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ELFKNAMRAT VESHESSLIL PPIKVMVALG EEDLSIKMSD RGGGVPLRKI

Homologie: Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against PDK2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 407 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Andere Bezeichnung: PDK2 (PDK2 Produkte)

Synonyme: PDHK2 antikoerper, PDKII antikoerper, Pdk antikoerper, zgc:56209 antikoerper, PDK2 antikoerper, pyruvate dehydrogenase kinase 2 antikoerper, pyruvate dehydrogenase kinase, isoenzyme 2 antikoerper, pyruvate dehydrogenase kinase, isozyme 2b antikoerper, PDK2 antikoerper, Pdk2 antikoerper, pdk2b antikoerper

Hintergrund: PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Alias Symbols: PDHK2
Protein Interaction Partner: VSIG4, DLAT, ISOC2, HIC2, SGK1, PDK2, PDK1, PDHA1, PDHX, AKT1, HTT,
Protein Size: 407

Molekulargewicht: 44 kDa

Gen-ID: 5164

NCBI Accession: NM_002611, NP_002602

UniProt: Q15119

Pathways: PI3K-Akt Signalweg, RTK Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt